Itraconazole · more major-labeled pairs than Dofetilide
SPL labels Itraconazole + Dofetilide as major; Itraconazole 19 / Dofetilide 4 in that band.
Mechanism on file: Itraconazole interferes with the way your body breaks down dofetilide, potentially causing the heart medication to reach dangerous levels.
FDA SPL severity: Major
Itraconazole + Dofetilide · SPL mechanism field
Itraconazole interferes with the way your body breaks down dofetilide, potentially causing the heart medication to reach dangerous levels.
Major band excerpt · Itraconazole with Dofetilide
Antiarrhythmics Disopyramide Dofetilide Dronedarone Quinidine a Contraindicated during and 2 weeks after itraconazole treatment.
Itraconazole · 19 major-labeled pairs (vs Dofetilide's 4)
- Atorvastatin major
- Colchicine major
- Dronedarone major
- Eplerenone major
Dofetilide · 4 major + 8 total pairs
- Bictegravir/Emtricitabine/Tenofovir major
- Dolutegravir major
- Dolutegravir/Lamivudine major
- Clarithromycin moderate
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.