Itraconazole · more major-labeled pairs than Atorvastatin
SPL labels Itraconazole + Atorvastatin as major; Itraconazole 19 / Atorvastatin 3 in that band.
Mechanism on file: Itraconazole prevents your body from breaking down atorvastatin normally, which increases the amount of medicine in your bloodstream.
FDA SPL severity: Major
Itraconazole + Atorvastatin · SPL mechanism field
Itraconazole prevents your body from breaking down atorvastatin normally, which increases the amount of medicine in your bloodstream.
Major band excerpt · Itraconazole with Atorvastatin
Intervention: In patients taking clarithromycin or itraconazole, do not exceed atorvastatin 20 mg [see Dosage and Administration (2.5) ]. Examples: Erythromycin, clarithromycin, itraconazole, ketoconazole, posaconazole, and voriconazole.
Itraconazole · 19 major-labeled pairs (vs Atorvastatin's 3)
- Colchicine major
- Dofetilide major
- Dronedarone major
- Eplerenone major
Atorvastatin · 3 major + 36 total pairs
- Clarithromycin major
- Darunavir major
- Amiodarone minor
- Bazedoxifene/Conjugated Estrogens minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.