Insulin Glulisine and Albuterol Interaction
Drug interaction information between Insulin Glulisine and Albuterol.
Insulin Glulisine and Albuterol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Insulin Glulisine and Albuterol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Albuterol can cause blood sugar levels to rise, which counteracts the effect of the insulin.
FDA Label Information
Drugs that May Decrease the Blood Glucose Lowering Effect of APIDRA Drugs: Atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, phenothiazine derivatives, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones.
Insulin Glulisine Also Interacts With
- Fluoxetine moderate
- Pramlintide moderate
- Octreotide moderate
- Clonidine minor
- Lithium minor
Albuterol Also Interacts With
- Theophylline major
- Albuterol/Ipratropium moderate
- Atomoxetine moderate
- Digoxin minor
- Glimepiride minor
Frequently Asked Questions
What SPL severity band is on file for Insulin Glulisine + Albuterol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Albuterol has 16 labeled pairs on file vs Insulin Glulisine's 9. In the minor band specifically: Insulin Glulisine has 6 (also Clonidine, Lithium, Epinephrine, Glucagon); Albuterol has 13 (also Digoxin, Glimepiride, Insulin Aspart, Insulin Degludec).
What mechanism field is on file for Insulin Glulisine and Albuterol?
Albuterol can cause blood sugar levels to rise, which counteracts the effect of the insulin.
Albuterol carries more major-labeled pairs than Insulin Glulisine
SPL source-record counts only. This page's band is minor · classes on file: Insulin Glulisine (Rapid-Acting Insulin); Albuterol (Short-Acting Beta-2 Agonist).
Albuterol has 1 major-labeled pair vs Insulin Glulisine's 0. This page itself is in the minor band, not the major band.
0 major · 3 moderate · 6 minor · 9 total
- Other minor peers for Insulin Glulisine
- Clonidine
- Lithium
- Epinephrine
- Glucagon
1 major · 2 moderate · 13 minor · 16 total
- Other minor peers for Albuterol
- Digoxin
- Glimepiride
- Insulin Aspart
- Insulin Degludec
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.