Fluconazole · more major-labeled pairs than Fluvastatin
SPL labels Fluvastatin + Fluconazole as moderate; Fluvastatin 6 / Fluconazole 7 in that band.
Mechanism on file: Fluconazole prevents your body from properly breaking down fluvastatin, which can cause the drug to reach levels that damage your muscles.
FDA SPL severity: Moderate
Fluvastatin + Fluconazole · SPL mechanism field
Fluconazole prevents your body from properly breaking down fluvastatin, which can cause the drug to reach levels that damage your muscles.
Moderate band excerpt · Fluvastatin with Fluconazole
HMG-CoA reductase inhibitors : The risk of myopathy and rhabdomyolysis increases when fluconazole is coadministered with HMG-CoA reductase inhibitors metabolized through CYP3A4, such as atorvastatin and simvastatin, or through CYP2C9, such as fluvastatin.
Fluvastatin · 6 moderate + 12 total pairs
- Cyclosporine moderate
- Gemfibrozil moderate
- Glyburide moderate
- Niacin moderate
Fluconazole · 3 major-labeled pairs (vs Fluvastatin's 1)
- Amiodarone moderate
- Atorvastatin moderate
- Carbamazepine moderate
- Lemborexant moderate
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.