Epinephrine · more major-labeled pairs than Glimepiride
SPL labels Epinephrine + Glimepiride as minor; Epinephrine 24 / Glimepiride 16 in that band.
Mechanism on file: Epinephrine is a stimulant that can raise blood sugar, which works against the blood sugar-lowering effect of glimepiride.
FDA SPL severity: Minor
Epinephrine + Glimepiride · SPL mechanism field
Epinephrine is a stimulant that can raise blood sugar, which works against the blood sugar-lowering effect of glimepiride.
Minor band excerpt · Epinephrine with Glimepiride
The following are examples of medications that may reduce the glucose-lowering effect of sulfonylureas including glimepiride, leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline), and isoniazid.
Epinephrine · 1 major-labeled pairs (vs Glimepiride's 0)
- Amitriptyline minor
- Atenolol minor
- Clonidine minor
- Dopamine minor
Glimepiride · 16 minor + 16 total pairs
- Albuterol minor
- Clarithromycin minor
- Clonidine minor
- Clozapine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.