Clozapine · larger labeled portfolio than Glimepiride
SPL labels Glimepiride + Clozapine as minor; Glimepiride 16 / Clozapine 39 in that band.
Mechanism on file: Clozapine can interfere with how well glimepiride works, which may cause your blood sugar levels to become too high.
FDA SPL severity: Minor
Glimepiride + Clozapine · SPL mechanism field
Clozapine can interfere with how well glimepiride works, which may cause your blood sugar levels to become too high.
Minor band excerpt · Glimepiride with Clozapine
The following are examples of medications that may reduce the glucose-lowering effect of sulfonylureas including glimepiride, leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline), and isoniazid.
Glimepiride · 16 minor + 16 total pairs
- Albuterol minor
- Clarithromycin minor
- Clonidine minor
- Colesevelam minor
Clozapine · 42 SPL pairs (broader portfolio than Glimepiride)
- Amiodarone minor
- Bupropion minor
- Carbamazepine minor
- Chlorpromazine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.