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What the FDA labels say about taking them together

Albuterol and glimepiride

Glimepiride's FDA label of May 12, 2025 names albuterol in its drug interactions section; the albuterol labels PlainMeds reads (4) do not name glimepiride. The glimepiride label: “The following are examples of medications that may reduce the glucose-lowering effect of sulfonylureas including glimepiride, leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors …”

Check it at the source: the albuterol FDA label on DailyMed (effective April 30, 2026, Ritedose Pharmaceuticals, LLC); the glimepiride FDA label on DailyMed (effective May 12, 2025, Micro Labs Limited).

What does the albuterol label say about glimepiride?

Albuterol's label (effective April 30, 2026) and its 3 other brand-application labels do not name glimepiride in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Albuterol Sulfate Inhalation Solution), Ritedose Pharmaceuticals, LLC, effective April 30, 2026 (SPL set d4c532be-1f41-60d3-e053-2995a90a98be), via openFDA; the full label on DailyMed

What does the glimepiride label say about albuterol?

Glimepiride label, drug interactions

The following are examples of medications that may reduce the glucose-lowering effect of sulfonylureas including glimepiride, leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid hormones, estrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics (e.g., epinephrine, albuterol, terbutaline), and isoniazid.

Source: FDA drug label (Glimepiride), Micro Labs Limited, effective May 12, 2025 (SPL set 60e9397e-83b9-489e-9683-6f87e458bbaa), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

40Albuterol generic labelers
27Glimepiride generic labelers
AlbuterolGlimepiride
Labeled forAsthmaType 2 diabetes
Boxed warningNoNo
Pharmacy cost (NADAC)$0.288 per tablet 2 mg tablet$0.0507 per tablet 4 mg tablet
Shortage nowResolvedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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