Phenytoin · more major-labeled pairs than Caspofungin
SPL labels Caspofungin + Phenytoin as minor; Caspofungin 6 / Phenytoin 120 in that band.
Mechanism on file: Phenytoin speeds up the way your liver processes caspofungin, which may reduce the medicine's ability to fight infection.
FDA SPL severity: Minor
Caspofungin + Phenytoin · SPL mechanism field
Phenytoin speeds up the way your liver processes caspofungin, which may reduce the medicine's ability to fight infection.
Minor band excerpt · Caspofungin with Phenytoin
Other Inducers of Hepatic CYP Enzymes Adults : When caspofungin is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of caspofungin should be considered [see Dosage and Administration ( 2.5 ) and Clinical Pharmacology ( 12.3 )] . Pediatric Patients : When caspofungin is co-administered to pediatric patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily...
Caspofungin · 6 minor + 6 total pairs
- Carbamazepine minor
- Cyclosporine minor
- Dexamethasone minor
- Rifampin minor
Phenytoin · 4 major-labeled pairs (vs Caspofungin's 0)
- Acarbose minor
- Acetaminophen/Oxycodone minor
- Albendazole minor
- Alogliptin minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.