Dexamethasone · larger labeled portfolio than Caspofungin
SPL labels Caspofungin + Dexamethasone as minor; Caspofungin 6 / Dexamethasone 18 in that band.
Mechanism on file: Dexamethasone triggers your liver to clear caspofungin from your system more quickly than it normally would.
FDA SPL severity: Minor
Caspofungin + Dexamethasone · SPL mechanism field
Dexamethasone triggers your liver to clear caspofungin from your system more quickly than it normally would.
Minor band excerpt · Caspofungin with Dexamethasone
Other Inducers of Hepatic CYP Enzymes Adults : When caspofungin is co-administered to adult patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily dose of 70 mg of caspofungin should be considered [see Dosage and Administration ( 2.5 ) and Clinical Pharmacology ( 12.3 )] . Pediatric Patients : When caspofungin is co-administered to pediatric patients with other inducers of hepatic CYP enzymes, such as efavirenz, nevirapine, phenytoin, dexamethasone, or carbamazepine, administration of a daily...
Caspofungin · 6 minor + 6 total pairs
- Carbamazepine minor
- Cyclosporine minor
- Phenytoin minor
- Rifampin minor
Dexamethasone · 21 SPL pairs (broader portfolio than Caspofungin)
- Albendazole minor
- Amphotericin B minor
- Aprepitant minor
- Carbamazepine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
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