Erythromycin · more major-labeled pairs than Buprenorphine
SPL labels Buprenorphine + Erythromycin as minor; Buprenorphine 19 / Erythromycin 53 in that band.
Mechanism on file: Erythromycin can lower the levels of pain medicine in your body by making your system process it faster than usual.
FDA SPL severity: Minor
Buprenorphine + Erythromycin · SPL mechanism field
Erythromycin can lower the levels of pain medicine in your body by making your system process it faster than usual.
Minor band excerpt · Buprenorphine with Erythromycin
Examples: Macrolide antibiotics (e.g., erythromycin), azole-antifungal agents (e.g., ketoconazole), protease inhibitors (e.g., ritonavir) CYP3A4 Inducers Clinical Impact: The concomitant use of BELBUCA and CYP3A4 inducers can decrease the plasma concentration of buprenorphine [see Clinical Pharmacology (12.3) ] , potentially resulting in decreased efficacy or onset of a withdrawal syndrome in patients who have developed physical dependence to buprenorphine.
Buprenorphine · 19 minor + 19 total pairs
- Buprenorphine minor
- Butorphanol minor
- Carbamazepine minor
- Cyclobenzaprine minor
Erythromycin · 4 major-labeled pairs (vs Buprenorphine's 0)
- Acetaminophen/Oxycodone minor
- Alprazolam minor
- Atorvastatin minor
- Bromocriptine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.