Buprenorphine · larger labeled portfolio than Butorphanol
SPL labels Buprenorphine + Butorphanol as minor; Buprenorphine 19 / Butorphanol 10 in that band.
Mechanism on file: These medicines can work together to slow your breathing and make your muscles very weak. This increases the risk of serious breathing problems.
FDA SPL severity: Minor
Buprenorphine + Butorphanol · SPL mechanism field
These medicines can work together to slow your breathing and make your muscles very weak. This increases the risk of serious breathing problems.
Minor band excerpt · Buprenorphine with Butorphanol
Examples: butorphanol, nalbuphine, pentazocine Muscle Relaxants Clinical Impact: Buprenorphine may enhance the neuromuscular blocking action of skeletal muscle relaxants and produce an increased degree of respiratory depression.
Buprenorphine · 19 SPL pairs (broader portfolio than Butorphanol)
- Buprenorphine minor
- Carbamazepine minor
- Cyclobenzaprine minor
- Erythromycin minor
Butorphanol · 10 minor + 11 total pairs
- Acetaminophen/Oxycodone minor
- Codeine minor
- Fentanyl minor
- Hydromorphone minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.