What the FDA labels say about taking them together
Ibandronate and ranitidine
Ibandronate's FDA label of March 18, 2026 names ranitidine in its drug interactions section; the ranitidine label PlainMeds reads does not name ibandronate. The ibandronate label: “H 2 Blockers In healthy volunteers, co-administration with ranitidine resulted in a 20% increased bioavailability of ibandronate, which was not considered to be clinically relevant.”
Check it at the source: the ibandronate FDA label on DailyMed (effective March 18, 2026, Aurobindo Pharma Limited); the ranitidine FDA label on DailyMed (effective May 1, 2026, Amneal Pharmaceuticals of New York LLC).
What does the ibandronate label say about ranitidine?
Ibandronate label, drug interactionsH 2 Blockers In healthy volunteers, co-administration with ranitidine resulted in a 20% increased bioavailability of ibandronate, which was not considered to be clinically relevant (see CLINICAL PHARMACOLOGY [12.3] ).
Source: FDA drug label (Ibandronate Sodium), Aurobindo Pharma Limited, effective March 18, 2026 (SPL set 86c0b4ae-5e38-4efe-88af-50ac560e294f), via openFDA; the full label on DailyMed
What does the ranitidine label say about ibandronate?
Ranitidine's label (effective May 1, 2026) does not name ibandronate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ranitidine), Amneal Pharmaceuticals of New York LLC, effective May 1, 2026 (SPL set b38a3332-5c54-453f-aeb7-070f830955c2), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ibandronate | Ranitidine | |
|---|---|---|
| Labeled for | Osteoporosis | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $2.68 per tablet 150 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once