Darunavir · more major-labeled pairs than Amitriptyline
SPL labels Amitriptyline + Darunavir as minor; Amitriptyline 20 / Darunavir 70 in that band.
Mechanism on file: Darunavir increases the amount of amitriptyline in your system, which can lead to side effects like nausea, dizziness, or fainting.
FDA SPL severity: Minor
Amitriptyline + Darunavir · SPL mechanism field
Darunavir increases the amount of amitriptyline in your system, which can lead to side effects like nausea, dizziness, or fainting.
Minor band excerpt · Amitriptyline with Darunavir
Tricyclic Antidepressants (TCAs): amitriptyline, desipramine, imipramine, nortriptyline ↑ amitriptyline ↑ desipramine ↑ imipramine ↑ nortriptyline Use a lower dose of the tricyclic antidepressants and trazodone due to potential increased adverse events such as nausea, dizziness, hypotension and syncope.
Amitriptyline · 20 minor + 21 total pairs
- Carbamazepine minor
- Cimetidine minor
- Clonidine minor
- Disulfiram minor
Darunavir · 15 major-labeled pairs (vs Amitriptyline's 1)
- Amiodarone minor
- Amlodipine minor
- Beclomethasone minor
- Buprenorphine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.