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What the FDA labels say about taking them together

Beclomethasone and darunavir

Darunavir's FDA label of August 29, 2025 names beclomethasone in its drug interactions section; the beclomethasone labels PlainMeds reads (2) do not name darunavir. The darunavir label: “… Cushing's syndrome and adrenal suppression. Alternative corticosteroids including beclomethasone, prednisone, and prednisolone should be considered, particularly for long term use.”

Check it at the source: the beclomethasone FDA label on DailyMed (effective June 25, 2024, A-S Medication Solutions); the darunavir FDA label on DailyMed (effective August 29, 2025, Janssen Products LP).

What does the beclomethasone label say about darunavir?

Beclomethasone's label (effective June 25, 2024) and its 1 other brand-application label do not name darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (QVAR REDIHALER), NDA207921 (Norton Waterford), as published by A-S Medication Solutions, effective June 25, 2024 (SPL set ccd3aaec-4892-40d0-ad60-3e570178fbe1), via openFDA; the full label on DailyMed

What does the darunavir label say about beclomethasone?

Darunavir label, drug interactions

Concomitant Drug Class Drug Name Examples: Corticosteroids primarily metabolized by CYP3A: e.g. betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone; Effect on Concentration of Darunavir Or Concomitant Drug: ↑ corticosteroids; Clinical Comment: Co-administration with corticosteroids (all routes of administration) of which exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression. …

Source: FDA drug label (PREZISTA), Janssen Products LP, effective August 29, 2025 (SPL set 814301f9-c990-46a5-b481-2879a521a16f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Beclomethasone generic labelers
13Darunavir generic labelers
BeclomethasoneDarunavir
Labeled forAsthma, AllergiesHIV
Boxed warningNoNo
Pharmacy cost (NADAC)$30.23 per gram 80 mcg nasal spray$1.16 per tablet 600 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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