Darunavir · more major-labeled pairs than Buprenorphine
SPL labels Darunavir + Buprenorphine as minor; Darunavir 70 / Buprenorphine 28 in that band.
Mechanism on file: Darunavir increases the amount of a byproduct created when your body processes buprenorphine.
FDA SPL severity: Minor
Darunavir + Buprenorphine · SPL mechanism field
Darunavir increases the amount of a byproduct created when your body processes buprenorphine.
Minor band excerpt · Darunavir with Buprenorphine
Narcotic analgesics/treatment of opioid dependence : buprenorphine, buprenorphine/naloxone ↔ buprenorphine, naloxone ↑ norbuprenorphine (metabolite) No dose adjustment for buprenorphine or buprenorphine/naloxone is required with concurrent administration of darunavir/ritonavir. Clinical monitoring is recommended if darunavir/ritonavir and buprenorphine or buprenorphine/naloxone are co-administered.
Darunavir · 15 major-labeled pairs (vs Buprenorphine's 0)
- Amiodarone minor
- Amitriptyline minor
- Amlodipine minor
- Beclomethasone minor
Buprenorphine · 28 minor + 29 total pairs
- Alprazolam minor
- Buprenorphine (Pain) minor
- Buprenorphine/Naloxone minor
- Carbamazepine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.