Alosetron · larger labeled portfolio than Eluxadoline
SPL labels Alosetron + Eluxadoline as minor; Alosetron 9 / Eluxadoline 2 in that band.
Mechanism on file: Eluxadoline can interfere with how your body breaks down alosetron, leading to higher amounts of alosetron in your bloodstream.
FDA SPL severity: Minor
Alosetron + Eluxadoline · SPL mechanism field
Eluxadoline can interfere with how your body breaks down alosetron, leading to higher amounts of alosetron in your bloodstream.
Minor band excerpt · Alosetron with Eluxadoline
Examples: alosetron, anticholinergics, opioids Table 3: Established and Other Potentially Clinically Relevant Interactions Affecting Drugs Co-Administered with VIBERZI OATP1B1 and BCRP Substrate Clinical Impact: VIBERZI may increase the exposure of co-administered OATP1B1 and BCRP substrates.
Alosetron · 12 SPL pairs (broader portfolio than Eluxadoline)
- Cimetidine minor
- Estradiol minor
- Fluvoxamine minor
- Hydralazine minor
Eluxadoline · 2 minor + 6 total pairs
- Cyclosporine minor
- Gemfibrozil moderate
- Loperamide moderate
- Rifampin moderate
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.