What the FDA labels say about taking them together
Clonidine and insulin aspart
Insulin aspart's FDA label of June 21, 2023 names clonidine in its drug interactions section; the clonidine labels PlainMeds reads (4) do not name insulin aspart. The insulin aspart label: “Drugs That May Increase or Decrease the Blood Glucose Lowering Effect of FIASP Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.”
Check it at the source: the clonidine FDA label on DailyMed (effective March 30, 2026, Unichem Pharmaceuticals (USA), Inc.); the insulin aspart FDA label on DailyMed (effective June 21, 2023, Novo Nordisk).
What does the clonidine label say about insulin aspart?
Clonidine's label (effective March 30, 2026) and its 3 other brand-application labels do not name insulin aspart in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (clonidine hydrochloride), Unichem Pharmaceuticals (USA), Inc., effective March 30, 2026 (SPL set 21bfa28f-20df-43fd-bb80-b720d3b40696), via openFDA; the full label on DailyMed
What does the insulin aspart label say about clonidine?
Insulin aspart label, drug interactionsDrugs That May Increase or Decrease the Blood Glucose Lowering Effect of FIASP Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.
Source: FDA drug label (Insulin Aspart, BLA020986), Novo Nordisk Pharma, Inc., effective February 28, 2023 (SPL set bee5b358-c863-420b-be73-ced2e920c499), via openFDA
Source: FDA drug label (Merilog, BLA761325), Sanofi-Aventis U.S. LLC, effective October 7, 2025 (SPL set eee07a52-1102-4d48-9782-26061db175ad), via openFDA
Source: FDA drug label (Insulin Aspart Protamine And Insulin Aspart Mix 70/30, BLA021172), Novo Nordisk Pharma, Inc., effective February 28, 2023 (SPL set fc94baa4-3606-48bc-a781-9617ab6960ef), via openFDA
Source: FDA drug label (Fiasp), Novo Nordisk, effective June 21, 2023 (SPL set 834e7efc-393f-4c55-9125-628562a8a5cf), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Clonidine | Insulin aspart | |
|---|---|---|
| Labeled for | High blood pressure, ADHD, Pain | Type 2 diabetes, Type 1 diabetes |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0241 per tablet 0.1 mg tablet | $6.95 per mL 100 unit/mL vial |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once