What the FDA labels say about taking them together
Anhydrous citric acid/magnesium oxide/sodium picosulfate and penicillamine
Anhydrous citric acid/magnesium oxide/sodium picosulfate's FDA label of April 15, 2026 names penicillamine in its drug interactions section; the penicillamine labels PlainMeds reads (2) do not name anhydrous citric acid/magnesium oxide/sodium picosulfate. The anhydrous citric acid/magnesium oxide/sodium picosulfate label: “Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with …”
Check it at the source: the anhydrous citric acid/magnesium oxide/sodium picosulfate FDA label on DailyMed (effective April 15, 2026); the penicillamine FDA label on DailyMed (effective January 26, 2026, Bausch Health US, LLC).
What does the anhydrous citric acid/magnesium oxide/sodium picosulfate label say about penicillamine?
Anhydrous citric acid/magnesium oxide/sodium picosulfate label, drug interactionsAdminister tetracycline and fluoroquinolone antibiotics [see Drug Interactions (7.3) ], iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium.
Source: FDA drug label (CLENPIQ), Ferring Pharmaceuticals Inc., effective April 15, 2026 (SPL set e95fff66-4ec0-4001-a727-33e66a5ec7d5), via openFDA; the full label on DailyMed
What does the penicillamine label say about anhydrous citric acid/magnesium oxide/sodium picosulfate?
Penicillamine's label (effective January 26, 2026) and its 1 other brand-application label do not name anhydrous citric acid/magnesium oxide/sodium picosulfate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cuprimine), NDA019853 (Valeant Pharms Intl), as published by Bausch Health US, LLC, effective January 26, 2026 (SPL set 80e736d3-2017-4d68-94b4-38255c3c59c6), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Anhydrous citric acid/magnesium oxide/sodium picosulfate | Penicillamine | |
|---|---|---|
| Labeled for | n/a | Rheumatoid arthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.518 per mL 175 mL solution | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once