What the FDA labels say about taking them together
Anhydrous citric acid/magnesium oxide/sodium picosulfate and digoxin
Anhydrous citric acid/magnesium oxide/sodium picosulfate's FDA label of April 15, 2026 names digoxin in its drug interactions section; the digoxin labels PlainMeds reads (3) do not name anhydrous citric acid/magnesium oxide/sodium picosulfate. The anhydrous citric acid/magnesium oxide/sodium picosulfate label: “Administer tetracycline and fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with …”
Check it at the source: the anhydrous citric acid/magnesium oxide/sodium picosulfate FDA label on DailyMed (effective April 15, 2026); the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.).
What does the anhydrous citric acid/magnesium oxide/sodium picosulfate label say about digoxin?
Anhydrous citric acid/magnesium oxide/sodium picosulfate label, drug interactionsAdminister tetracycline and fluoroquinolone antibiotics [see Drug Interactions (7.3) ], iron, digoxin, chlorpromazine, and penicillamine at least 2 hours before and not less than 6 hours after administration of CLENPIQ to avoid chelation with magnesium.
Source: FDA drug label (CLENPIQ), Ferring Pharmaceuticals Inc., effective April 15, 2026 (SPL set e95fff66-4ec0-4001-a727-33e66a5ec7d5), via openFDA; the full label on DailyMed
What does the digoxin label say about anhydrous citric acid/magnesium oxide/sodium picosulfate?
Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name anhydrous citric acid/magnesium oxide/sodium picosulfate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Anhydrous citric acid/magnesium oxide/sodium picosulfate | Digoxin | |
|---|---|---|
| Labeled for | n/a | Heart failure, Atrial fibrillation |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.518 per mL 175 mL solution | $0.133 per tablet 125 mcg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once