HIGH-VOLUME · HOSP-HEAVY
warfarin Side Effects
warfarin (also sold as Coumadin, Jantoven) is HIGH-VOLUME in this FAERS book #60 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 45.8% mention hospitalization (57,230 reports).
Data updated 2026-05-15
- 124,873
- FAERS reports
FAERS voluntary reports, 1999 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
warfarin: 45.8% mention hospitalization (57,230 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #60 of 524 by FAERS report count.
High-report extract for warfarin (Coumadin): 124,873 FAERS rows (1999-2025). Top named reactions: INTERNATIONAL NORMALISED RATIO INCREASED, DYSPNOEA, DRUG INTERACTION. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1999–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
INTERNATIONAL NORMALISED RATIO INCREASED leads 10,276 of 124,873 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (32,010 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (15,949 reports, 12.8%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 4,705 |
| DYSPNOEA | 1,178 |
| PNEUMONIA | 1,052 |
| SEPSIS | 950 |
| INTERNATIONAL NORMALISED RATIO INCREASED | 885 |
| NAUSEA | 834 |
| FALL | 764 |
| HYPOTENSION | 735 |
| CARDIAC ARREST | 725 |
| VOMITING | 690 |
| CARDIAC FAILURE | 674 |
| RENAL FAILURE | 660 |
| CEREBRAL HAEMORRHAGE | 653 |
| ANAEMIA | 616 |
| COMPLETED SUICIDE | 606 |
| ASTHENIA | 602 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 599 |
| DRUG INTERACTION | 592 |
| RESPIRATORY FAILURE | 592 |
| CONDITION AGGRAVATED | 576 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (57,230, 45.8% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| INTERNATIONAL NORMALISED RATIO INCREASED | 6,599 |
| DYSPNOEA | 5,185 |
| PNEUMONIA | 3,342 |
| FALL | 3,308 |
| DRUG INTERACTION | 3,237 |
| ANAEMIA | 2,957 |
| NAUSEA | 2,832 |
| DIARRHOEA | 2,733 |
| ASTHENIA | 2,678 |
| FATIGUE | 2,509 |
| DIZZINESS | 2,430 |
| HYPOTENSION | 2,392 |
| GASTROINTESTINAL HAEMORRHAGE | 2,390 |
| ATRIAL FIBRILLATION | 2,320 |
| HAEMORRHAGE | 2,295 |
| VOMITING | 2,154 |
| HAEMOGLOBIN DECREASED | 2,126 |
| HEADACHE | 1,895 |
| MALAISE | 1,881 |
| ACUTE KIDNEY INJURY | 1,813 |
How to read warfarin FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 124,873 voluntary reports linked to warfarin (Coumadin, Jantoven), 1999-2025. Death is listed on 15,949 (12.8%). Hospitalization appears on 57,230 (45.8%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with warfarin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 127,196 FAERS cases (Δ 2,323 heavier vs warfarin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 127,698 FAERS cases (Δ 2,825 heavier vs warfarin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 128,099 FAERS cases (Δ 3,226 heavier vs warfarin); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 121,298 FAERS cases (Δ 3,575 lighter vs warfarin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.3 pp vs warfarin's DEATH-HEAVY): CASELOAD · HOSP-MID.
warfarin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.