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Drug side effects

valsartan Side Effects

The reactions most often reported to the FDA for valsartan (also sold as Diovan), with demographics, serious outcomes, and reporting trends.

Data updated 2026-05-15

102,306
FAERS reports

Data from the FDA Adverse Event Reporting System (FAERS), 2001 to 2025. A FAERS report records a temporal association, not proof of cause. See our methodology for how figures are compiled and de-duplicated.

The most commonly reported side effects of valsartan come from 102,306 reports to the FDA, broken down here by frequency, patient demographics, and serious outcomes.

This page analyzes 102,306 reports to the FDA Adverse Event Reporting System (FAERS) for valsartan (Diovan): the reactions reported most often, who reported them, serious outcomes such as hospitalization, and year-over-year trends. A FAERS report does not prove the drug caused the effect, and report volume tracks how widely a drug is used, not how likely an effect is for any one person. Educational information, not medical advice.

Total Reports

102,306

Reports Mentioning Death

9,430

9.2% of reports — not proof the medicine caused the death

Hospitalizations

38,453

37.6% of reports

Top Indication

Hypertension

Most Reported Adverse Reactions

FATIGUE
5,474
DYSPNOEA
5,250
DIZZINESS
5,249
NAUSEA
5,162
DIARRHOEA
4,578
HEADACHE
4,504
HYPERTENSION
4,273
BLOOD PRESSURE INCREASED
4,207
PAIN
3,810
FALL
3,601
ASTHENIA
3,587
MALAISE
3,586
ACUTE KIDNEY INJURY
3,145
ARTHRALGIA
2,971
COUGH
2,897
VOMITING
2,889
PNEUMONIA
2,840
WEIGHT DECREASED
2,834

Who Reports Side Effects

Gender Distribution

Female 56,198 (59%)
Male 39,600 (41%)
Unknown 153

Age Distribution

0-17 498 (1%)
18-44 2,803 (4%)
45-64 21,292 (33%)
65-74 19,337 (30%)
75+ 20,526 (32%)

Reporting Trend by Year

2001 2025

Reactions in Death Reports

Top reactions reported in 9,430 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DEATH 2,734
PNEUMONIA 640
RENAL FAILURE 556
DYSPNOEA 479
MYOCARDIAL INFARCTION 441
CARDIAC ARREST 427
ACUTE KIDNEY INJURY 404
SEPSIS 374
CARDIAC FAILURE 362
DIARRHOEA 349
RESPIRATORY FAILURE 344
CEREBROVASCULAR ACCIDENT 330
CHRONIC KIDNEY DISEASE 329
FALL 324
ASTHENIA 318
HYPOTENSION 312
GENERAL PHYSICAL HEALTH DETERIORATION 296
CARDIO-RESPIRATORY ARREST 294
NAUSEA 293
HYPERTENSION 276

Reactions in Hospitalization Reports

Top reactions in 38,453 reports where hospitalization was an outcome.

Reaction Reports
DYSPNOEA 2,881
FALL 2,245
NAUSEA 2,238
PNEUMONIA 2,143
DIZZINESS 2,048
DIARRHOEA 2,032
FATIGUE 1,969
HYPERTENSION 1,909
ASTHENIA 1,845
ACUTE KIDNEY INJURY 1,824
ANAEMIA 1,789
PYREXIA 1,726
HYPOTENSION 1,698
VOMITING 1,637
PAIN 1,627
MALAISE 1,620
HEADACHE 1,529
MYOCARDIAL INFARCTION 1,416
WEIGHT DECREASED 1,409

Compare valsartan vs acebutolol →

What the FAERS Data Reveals About valsartan Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 102,306 voluntary reports linked to valsartan and its brand equivalents (Diovan), spanning 2001 through 2025. Of those, 9,430 (9.2%) listed death as an outcome and 38,453 (37.6%) involved hospitalization. The most common indication reported alongside adverse events was Hypertension.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 59% were female and 41% male; age distribution skews toward 45-64, with 21,292 reports in that bracket. The single most reported reaction is fatigue with 5,474 submissions, followed by dyspnoea and dizziness.

How to read these numbers

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice, speak with a licensed clinician about any side-effect concerns.