HIGH-VOLUME · HOSP-HEAVY
amlodipine Side Effects
amlodipine (also sold as Norvasc) is HIGH-VOLUME in this FAERS book #18 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 40.3% mention hospitalization (104,040 reports).
Data updated 2026-05-15
- 257,862
- FAERS reports
FAERS voluntary reports, 2003 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
amlodipine: 40.3% mention hospitalization (104,040 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #18 of 524 by FAERS report count.
High-report extract for amlodipine (Norvasc): 257,862 FAERS rows (2003-2025). Top named reactions: FATIGUE, DIARRHOEA, NAUSEA. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2003–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 15,697 of 257,862 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (59,928 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (28,135 reports, 10.9%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 7,743 |
| COMPLETED SUICIDE | 5,086 |
| TOXICITY TO VARIOUS AGENTS | 2,638 |
| PNEUMONIA | 1,371 |
| ACUTE KIDNEY INJURY | 1,341 |
| CARDIAC ARREST | 1,235 |
| DYSPNOEA | 1,166 |
| HYPOTENSION | 1,065 |
| RENAL FAILURE | 988 |
| SEPSIS | 967 |
| DIARRHOEA | 963 |
| NAUSEA | 825 |
| ASTHENIA | 759 |
| FATIGUE | 753 |
| VOMITING | 750 |
| CARDIO-RESPIRATORY ARREST | 745 |
| RESPIRATORY FAILURE | 743 |
| FALL | 680 |
| DECREASED APPETITE | 671 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (104,040, 40.3% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DYSPNOEA | 7,038 |
| ACUTE KIDNEY INJURY | 6,232 |
| HYPOTENSION | 6,099 |
| DIARRHOEA | 5,849 |
| PNEUMONIA | 5,830 |
| FALL | 5,823 |
| NAUSEA | 5,689 |
| FATIGUE | 5,147 |
| VOMITING | 5,039 |
| ASTHENIA | 4,309 |
| DIZZINESS | 4,029 |
| TOXICITY TO VARIOUS AGENTS | 3,936 |
| PYREXIA | 3,863 |
| MALAISE | 3,718 |
| HYPERTENSION | 3,689 |
| PAIN | 3,553 |
| HEADACHE | 3,325 |
| ANAEMIA | 3,281 |
How to read amlodipine FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 257,862 voluntary reports linked to amlodipine (Norvasc), 2003-2025. Death is listed on 28,135 (10.9%). Hospitalization appears on 104,040 (40.3%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with amlodipine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 262,453 FAERS cases (Δ 4,591 heavier vs amlodipine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 264,092 FAERS cases (Δ 6,230 heavier vs amlodipine); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 246,252 FAERS cases (Δ 11,610 lighter vs amlodipine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 245,754 FAERS cases (Δ 12,108 lighter vs amlodipine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.2 pp vs amlodipine's DEATH-HEAVY): CASELOAD · HOSP-MID.
amlodipine stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.