HIGH-VOLUME · HOSP-MID
cyclosporine Side Effects
cyclosporine (also sold as Neoral, Sandimmune) is HIGH-VOLUME in this FAERS book #72 of 524 by FAERS report count. Signature opener: HOSP-MID - 25.6% mention hospitalization (27,207 reports).
Data updated 2026-05-15
- 106,440
- FAERS reports
FAERS voluntary reports, 1994 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
cyclosporine: 25.6% mention hospitalization (27,207 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #72 of 524 by FAERS report count.
High-report extract for cyclosporine (Neoral): 106,440 FAERS rows (1994-2025). Top named reactions: EYE IRRITATION, PYREXIA, EYE PAIN. Outcome stamps DEATH-HEAVY · HOSP-MID · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1994–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
EYE IRRITATION leads 7,786 of 106,440 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (23,625 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (13,961 reports, 13.1%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 2,411 |
| SEPSIS | 1,229 |
| PNEUMONIA | 1,079 |
| PYREXIA | 985 |
| RESPIRATORY FAILURE | 793 |
| INFECTION | 750 |
| GRAFT VERSUS HOST DISEASE | 745 |
| SEPTIC SHOCK | 735 |
| CYTOMEGALOVIRUS INFECTION | 714 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 697 |
| MULTI-ORGAN FAILURE | 564 |
| RENAL FAILURE | 533 |
| ACUTE GRAFT VERSUS HOST DISEASE | 499 |
| DIARRHOEA | 483 |
| DYSPNOEA | 439 |
| EPSTEIN-BARR VIRUS INFECTION | 387 |
| RENAL IMPAIRMENT | 378 |
Reactions in Hospitalization Reports
Hospitalization mid-share (27,207, 25.6%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| PYREXIA | 2,529 |
| PNEUMONIA | 1,662 |
| DIARRHOEA | 1,558 |
| NAUSEA | 1,418 |
| DYSPNOEA | 1,326 |
| VOMITING | 1,248 |
| HEADACHE | 1,170 |
| FATIGUE | 1,168 |
| BLOOD CREATININE INCREASED | 1,163 |
| CONDITION AGGRAVATED | 1,069 |
| SEPSIS | 1,064 |
| PAIN | 1,046 |
| ACUTE KIDNEY INJURY | 1,027 |
| HYPERTENSION | 983 |
| RENAL FAILURE | 966 |
| ANAEMIA | 945 |
| MALAISE | 926 |
How to read cyclosporine FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-MID)
FAERS holds 106,440 voluntary reports linked to cyclosporine (Neoral, Sandimmune, Restasis), 1994-2025. Death is listed on 13,961 (13.1%). Hospitalization appears on 27,207 (25.6%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-MID is the page opener, not a per-patient risk.
Read with cyclosporine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 104,378 FAERS cases (Δ 2,062 lighter vs cyclosporine); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 109,144 FAERS cases (Δ 2,704 heavier vs cyclosporine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 103,356 FAERS cases (Δ 3,084 lighter vs cyclosporine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 103,354 FAERS cases (Δ 3,086 lighter vs cyclosporine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.0 pp vs cyclosporine's DEATH-HEAVY): CASELOAD · HOSP-MID.
cyclosporine stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.