HIGH-VOLUME · HOSP-HEAVY
sertraline Side Effects
sertraline (also sold as Zoloft) is HIGH-VOLUME in this FAERS book #67 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 34.3% mention hospitalization (38,447 reports).
Data updated 2026-05-15
- 112,198
- FAERS reports
FAERS voluntary reports, 2004 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
sertraline: 34.3% mention hospitalization (38,447 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #67 of 524 by FAERS report count.
High-report extract for sertraline (Zoloft): 112,198 FAERS rows (2004-2025). Top named reactions: NAUSEA, FATIGUE, DIARRHOEA. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2004–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 6,466 of 112,198 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (25,942 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (11,431 reports, 10.2%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 2,644 |
| COMPLETED SUICIDE | 2,450 |
| TOXICITY TO VARIOUS AGENTS | 1,769 |
| DRUG ABUSE | 829 |
| CARDIO-RESPIRATORY ARREST | 632 |
| CARDIAC ARREST | 619 |
| DRUG INTERACTION | 472 |
| PNEUMONIA | 467 |
| OVERDOSE | 425 |
| FALL | 422 |
| DYSPNOEA | 409 |
| RESPIRATORY ARREST | 349 |
| SEPSIS | 336 |
| VOMITING | 319 |
| DIARRHOEA | 295 |
| NAUSEA | 290 |
| FATIGUE | 285 |
| ASTHENIA | 270 |
| SOMNOLENCE | 263 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (38,447, 34.3% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NAUSEA | 2,263 |
| DRUG INTERACTION | 2,192 |
| VOMITING | 2,181 |
| FALL | 2,166 |
| INTENTIONAL OVERDOSE | 2,008 |
| PNEUMONIA | 1,748 |
| DYSPNOEA | 1,667 |
| FATIGUE | 1,634 |
| TOXICITY TO VARIOUS AGENTS | 1,605 |
| DIARRHOEA | 1,604 |
| CONFUSIONAL STATE | 1,471 |
| DIZZINESS | 1,467 |
| ANXIETY | 1,438 |
| HEADACHE | 1,404 |
| SUICIDE ATTEMPT | 1,398 |
| ASTHENIA | 1,360 |
| CONDITION AGGRAVATED | 1,259 |
| DEPRESSION | 1,243 |
How to read sertraline FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 112,198 voluntary reports linked to sertraline (Zoloft), 2004-2025. Death is listed on 11,431 (10.2%). Hospitalization appears on 38,447 (34.3%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with sertraline
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 111,257 FAERS cases (Δ 941 lighter vs sertraline); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 113,967 FAERS cases (Δ 1,769 heavier vs sertraline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 110,018 FAERS cases (Δ 2,180 lighter vs sertraline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 109,698 FAERS cases (Δ 2,500 lighter vs sertraline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.9 pp vs sertraline's DEATH-HEAVY): CASELOAD · HOSP-MID.
sertraline stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.