HIGH-VOLUME · HOSP-HEAVY

famotidine Side Effects

famotidine (also sold as Pepcid) is HIGH-VOLUME in this FAERS book #69 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 32.4% mention hospitalization (35,591 reports).

Data updated 2026-05-15

110,018
FAERS reports

FAERS voluntary reports, 1995 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.

famotidine: 32.4% mention hospitalization (35,591 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #69 of 524 by FAERS report count.

High-report extract for famotidine (Pepcid): 110,018 FAERS rows (1995-2025). Top named reactions: NAUSEA, FATIGUE, CHRONIC KIDNEY DISEASE. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.

Counts from the openFDA FAERS extract (1995–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.

NAUSEA leads 7,258 of 110,018 reports

NAUSEA
7,258
FATIGUE
6,866
CHRONIC KIDNEY DISEASE
6,644
DIARRHOEA
6,452
DYSPNOEA
5,202
HEADACHE
4,907
ACUTE KIDNEY INJURY
4,660
PAIN
4,619
VOMITING
4,464
DIZZINESS
4,226
RENAL FAILURE
4,104
DEATH
3,690
PNEUMONIA
3,504
ASTHENIA
3,363
PYREXIA
3,343
RASH
3,183
ARTHRALGIA
3,138
PRURITUS
2,974

Who reports · age peak 45-64 (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 61,566 (62%)
Male 37,547 (38%)
Unknown 106

Age peak 45-64 (23,580 reports)

0-17 4,064 (6%)
18-44 10,919 (16%)
45-64 23,580 (34%)
65-74 16,749 (24%)
75+ 13,846 (20%)

FAERS filings rising toward 2025

1995 2025

Reactions in Death Reports

Death-mentioned subset is HEAVY here (10,287 reports, 9.4%). Top co-reported reactions in that subset - voluntary, not causal.

Reaction Reports
DEATH 3,672
PNEUMONIA 726
RENAL FAILURE 724
CHRONIC KIDNEY DISEASE 715
ACUTE KIDNEY INJURY 712
SEPSIS 585
RESPIRATORY FAILURE 535
DYSPNOEA 486
NAUSEA 464
END STAGE RENAL DISEASE 462
DIARRHOEA 452
PYREXIA 449
CARDIAC ARREST 420
ANAEMIA 408
FATIGUE 403
HYPOTENSION 386
ASTHENIA 364
DISEASE PROGRESSION 358
VOMITING 342

Reactions in Hospitalization Reports

Hospitalization is HEAVY (35,591, 32.4% of the book). Top reactions in those rows:

Reaction Reports
PNEUMONIA 2,739
NAUSEA 2,675
DIARRHOEA 2,463
DYSPNOEA 2,438
VOMITING 2,230
PYREXIA 2,147
FATIGUE 2,073
PAIN 1,720
FALL 1,713
ACUTE KIDNEY INJURY 1,690
ASTHENIA 1,604
HEADACHE 1,428
RENAL FAILURE 1,400
ANAEMIA 1,356
URINARY TRACT INFECTION 1,323
DIZZINESS 1,321
DEHYDRATION 1,298
ABDOMINAL PAIN 1,286
DECREASED APPETITE 1,170
How to read famotidine FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY)

FAERS holds 110,018 voluntary reports linked to famotidine (Pepcid), 1995-2025. Death is listed on 10,287 (9.4%). Hospitalization appears on 35,591 (32.4%). Top co-reported indication: Product Used For Unknown Indication.

MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.

Read with famotidine

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.