LOW-VOLUME · HOSP-HEAVY
pimozide Side Effects
pimozide (also sold as Orap) is a LOW-VOLUME FAERS extract #509 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 37.4% mention hospitalization (173 reports).
Data updated 2026-05-15
- 463
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
pimozide: 37.4% mention hospitalization (173 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #509 of 524 by FAERS report count.
Thinner FAERS extract for pimozide (Orap) (463 reports #509 of 524 by FAERS report count). 37.4% mention hospitalization (173 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DRUG INTERACTION leads 76 of 463 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (108 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (79 reports, 17.1%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DRUG INTERACTION | 20 |
| DEATH | 16 |
| TOXICITY TO VARIOUS AGENTS | 14 |
| CARDIO-RESPIRATORY ARREST | 13 |
| DYSMORPHISM | 12 |
| ATRIOVENTRICULAR SEPTAL DEFECT | 11 |
| FOETAL EXPOSURE DURING PREGNANCY | 10 |
| CARDIAC ARREST | 8 |
| COMPLETED SUICIDE | 8 |
| FOETAL DEATH | 8 |
| MEGACOLON | 7 |
| ARRHYTHMIA | 6 |
| HYPERTELORISM OF ORBIT | 6 |
| SUDDEN CARDIAC DEATH | 6 |
| EXTRAPYRAMIDAL DISORDER | 5 |
| ILEUS PARALYTIC | 5 |
| PLACENTAL INFARCTION | 5 |
| CARDIAC FAILURE | 4 |
| END STAGE RENAL DISEASE | 4 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (173, 37.4% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NEUROLEPTIC MALIGNANT SYNDROME | 24 |
| DRUG INTERACTION | 23 |
| PARKINSONISM | 18 |
| WEIGHT INCREASED | 17 |
| ELECTROCARDIOGRAM QT PROLONGED | 15 |
| SUICIDE ATTEMPT | 13 |
| CONDITION AGGRAVATED | 12 |
| FALL | 11 |
| EXTRAPYRAMIDAL DISORDER | 10 |
| FATIGUE | 10 |
| TOXICITY TO VARIOUS AGENTS | 10 |
| HYPOTENSION | 9 |
| LETHARGY | 9 |
| TIC | 9 |
| ANXIETY | 8 |
| CATATONIA | 8 |
| DEPRESSION | 8 |
| DIARRHOEA | 8 |
How to read pimozide FAERS figures (TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 463 voluntary reports linked to pimozide (Orap), 2004-2025. Death is listed on 79 (17.1%). Hospitalization appears on 173 (37.4%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with pimozide
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 408 FAERS cases (Δ 55 lighter vs pimozide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 520 FAERS cases (Δ 57 heavier vs pimozide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 531 FAERS cases (Δ 68 heavier vs pimozide); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 537 FAERS cases (Δ 74 heavier vs pimozide); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 45.0 pp vs pimozide's DEATH-HEAVY): CASELOAD · HOSP-MID.
pimozide stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload TRACE-CASE and the label guide.