LOW-VOLUME · HOSP-HEAVY
ethacrynic acid Side Effects
ethacrynic acid (also sold as Edecrin) is a LOW-VOLUME FAERS extract #508 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 40.8% mention hospitalization (212 reports).
Data updated 2026-05-15
- 520
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
ethacrynic acid: 40.8% mention hospitalization (212 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #508 of 524 by FAERS report count.
Thinner FAERS extract for ethacrynic acid (Edecrin) (520 reports #508 of 524 by FAERS report count). 40.8% mention hospitalization (212 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (1997–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS leads 59 of 520 reports
Who reports · age peak 65-74 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 65-74 (132 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (64 reports, 12.3%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 24 |
| FATIGUE | 9 |
| PYREXIA | 9 |
| CONSTIPATION | 6 |
| RESPIRATORY DISTRESS | 6 |
| TOXIC EPIDERMAL NECROLYSIS | 6 |
| VOMITING | 6 |
| ACUTE KIDNEY INJURY | 5 |
| APLASIA PURE RED CELL | 5 |
| ASPIRATION | 5 |
| CARDIAC FAILURE | 5 |
| DEVELOPMENTAL DELAY | 5 |
| ENTEROCOCCAL INFECTION | 5 |
| HAEMOGLOBIN DECREASED | 5 |
| LYMPHOCYTOSIS | 5 |
| NO THERAPEUTIC RESPONSE | 5 |
| RASH | 5 |
| STAPHYLOCOCCAL INFECTION | 5 |
| TRANSPLANT REJECTION | 5 |
| WHEEZING | 5 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (212, 40.8% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DRUG REACTION WITH EOSINOPHILIA AND SYSTEMIC SYMPTOMS | 46 |
| PNEUMONIA | 19 |
| ACUTE KIDNEY INJURY | 18 |
| DIARRHOEA | 18 |
| DYSPNOEA | 18 |
| DRUG HYPERSENSITIVITY | 17 |
| FATIGUE | 16 |
| NAUSEA | 14 |
| MALAISE | 13 |
| ASTHENIA | 12 |
| HYPOTENSION | 11 |
| PYREXIA | 11 |
| WEIGHT DECREASED | 11 |
| SEPSIS | 10 |
| VOMITING | 10 |
| ANAEMIA | 9 |
| CARDIAC FAILURE | 9 |
How to read ethacrynic acid FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 520 voluntary reports linked to ethacrynic acid (Edecrin), 1997-2025. Death is listed on 64 (12.3%). Hospitalization appears on 212 (40.8%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with ethacrynic acid
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 531 FAERS cases (Δ 11 heavier vs ethacrynic acid); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 537 FAERS cases (Δ 17 heavier vs ethacrynic acid); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 541 FAERS cases (Δ 21 heavier vs ethacrynic acid); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 463 FAERS cases (Δ 57 lighter vs ethacrynic acid); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.8 pp vs ethacrynic acid's DEATH-HEAVY): CASELOAD · HOSP-MID.
ethacrynic acid stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.