LOW-VOLUME · HOSP-HEAVY
dantrolene Side Effects
dantrolene (also sold as Dantrium) is a LOW-VOLUME FAERS extract #504 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 49.7% mention hospitalization (288 reports).
Data updated 2026-05-15
- 580
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
dantrolene: 49.7% mention hospitalization (288 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #504 of 524 by FAERS report count.
Thinner FAERS extract for dantrolene (Dantrium) (580 reports #504 of 524 by FAERS report count). 49.7% mention hospitalization (288 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NEUROLEPTIC MALIGNANT SYNDROME leads 81 of 580 reports
Who reports · age peak 18-44 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 18-44 (150 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (71 reports, 12.2%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| NEUROLEPTIC MALIGNANT SYNDROME | 21 |
| DEATH | 15 |
| HAEMODYNAMIC INSTABILITY | 9 |
| CARDIAC ARREST | 8 |
| HYPERKALAEMIA | 8 |
| HYPERTHERMIA MALIGNANT | 7 |
| FATIGUE | 6 |
| GLOMERULAR FILTRATION RATE ABNORMAL | 6 |
| HYPERTENSION | 6 |
| HYPERTHERMIA | 6 |
| LABILE BLOOD PRESSURE | 6 |
| PYREXIA | 6 |
| RHABDOMYOLYSIS | 6 |
| TACHYCARDIA | 6 |
| DRUG INTERACTION | 5 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 5 |
| RENAL FAILURE | 5 |
| RESPIRATORY FAILURE | 5 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (288, 49.7% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NEUROLEPTIC MALIGNANT SYNDROME | 67 |
| PYREXIA | 24 |
| HYPERTHERMIA | 23 |
| RHABDOMYOLYSIS | 21 |
| MUSCLE RIGIDITY | 20 |
| TACHYCARDIA | 20 |
| TREMOR | 19 |
| HYPERTENSION | 18 |
| TOXICITY TO VARIOUS AGENTS | 18 |
| DRUG INTERACTION | 16 |
| AGITATION | 14 |
| DRUG INEFFECTIVE FOR UNAPPROVED INDICATION | 14 |
| FALL | 14 |
| FATIGUE | 14 |
| PNEUMONIA | 14 |
| HYPOTENSION | 13 |
| URINARY TRACT INFECTION | 13 |
| ASTHENIA | 11 |
How to read dantrolene FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 580 voluntary reports linked to dantrolene (Dantrium), 2004-2025. Death is listed on 71 (12.2%). Hospitalization appears on 288 (49.7%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with dantrolene
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 596 FAERS cases (Δ 16 heavier vs dantrolene); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 541 FAERS cases (Δ 39 lighter vs dantrolene); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 537 FAERS cases (Δ 43 lighter vs dantrolene); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 531 FAERS cases (Δ 49 lighter vs dantrolene); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 49.9 pp vs dantrolene's DEATH-HEAVY): CASELOAD · HOSP-MID.
dantrolene stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.