LOW-VOLUME · HOSP-HEAVY
mexiletine Side Effects
mexiletine (also sold as Mexitil) is a LOW-VOLUME FAERS extract #510 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 62.0% mention hospitalization (253 reports).
Data updated 2026-05-15
- 408
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
mexiletine: 62.0% mention hospitalization (253 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #510 of 524 by FAERS report count.
Thinner FAERS extract for mexiletine (Mexitil) (408 reports #510 of 524 by FAERS report count). 62.0% mention hospitalization (253 reports). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 31 of 408 reports
Who reports · age peak 75+ (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 75+ (107 reports)
Reporting taper since 2004 peak
Reactions in Death Reports
Death-mentioned subset is HEAVY here (75 reports, 18.4%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| PNEUMONIA | 11 |
| DEATH | 10 |
| CARDIAC ARREST | 8 |
| CARDIAC FAILURE | 8 |
| NAUSEA | 8 |
| CARDIAC FAILURE CONGESTIVE | 7 |
| PAIN | 7 |
| DYSPNOEA | 6 |
| RENAL FAILURE | 6 |
| THROMBOCYTOPENIA | 6 |
| VOMITING | 6 |
| ANAEMIA | 5 |
| ANXIETY | 5 |
| ECONOMIC PROBLEM | 5 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 5 |
| RESPIRATORY FAILURE | 5 |
| VENTRICULAR TACHYCARDIA | 5 |
| ASTHENIA | 4 |
| HEADACHE | 4 |
| HYPERTENSION | 4 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (253, 62.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| FATIGUE | 31 |
| POOR QUALITY SLEEP | 24 |
| IMPAIRED WORK ABILITY | 23 |
| IMPAIRED QUALITY OF LIFE | 22 |
| DYSPNOEA | 20 |
| VENTRICULAR TACHYCARDIA | 20 |
| PYREXIA | 18 |
| HYPERTENSION | 17 |
| PNEUMONIA | 15 |
| CONTUSION | 13 |
| HERPES ZOSTER | 13 |
| NAUSEA | 13 |
| CARDIAC FAILURE | 12 |
| CARDIAC FAILURE CONGESTIVE | 12 |
| CATARACT | 12 |
| INSOMNIA | 12 |
| RESPIRATORY FAILURE | 12 |
| WEIGHT INCREASED | 12 |
| ALANINE AMINOTRANSFERASE INCREASED | 11 |
How to read mexiletine FAERS figures (TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 408 voluntary reports linked to mexiletine (Mexitil), 2004-2025. Death is listed on 75 (18.4%). Hospitalization appears on 253 (62.0%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with mexiletine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 463 FAERS cases (Δ 55 heavier vs mexiletine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 329 FAERS cases (Δ 79 lighter vs mexiletine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 318 FAERS cases (Δ 90 lighter vs mexiletine); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 299 FAERS cases (Δ 109 lighter vs mexiletine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's TRACE-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 43.7 pp vs mexiletine's DEATH-HEAVY): CASELOAD · HOSP-MID.
mexiletine stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload TRACE-CASE and the label guide.