HIGH-VOLUME · HOSP-HEAVY
melatonin Side Effects
melatonin (also sold as Melatonin) is HIGH-VOLUME in this FAERS book #139 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 33.6% mention hospitalization (17,241 reports).
Data updated 2026-05-15
- 51,370
- FAERS reports
FAERS voluntary reports, 2004 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
melatonin: 33.6% mention hospitalization (17,241 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #139 of 524 by FAERS report count.
High-report extract for melatonin (Melatonin): 51,370 FAERS rows (2004-2025). Top named reactions: FATIGUE, NAUSEA, DIARRHOEA. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2004–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 4,196 of 51,370 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (9,463 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (4,506 reports, 8.8%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 2,028 |
| SEPSIS | 361 |
| NAUSEA | 343 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 329 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 328 |
| VOMITING | 318 |
| COMPLETED SUICIDE | 310 |
| CONSTIPATION | 303 |
| ABDOMINAL PAIN | 291 |
| HYPONATRAEMIA | 288 |
| PNEUMONIA | 285 |
| ABDOMINAL DISTENSION | 281 |
| ASCITES | 272 |
| DYSPNOEA | 256 |
| CARDIOGENIC SHOCK | 255 |
| STRESS | 249 |
| CARDIAC ARREST | 247 |
| APPENDICITIS | 246 |
| APPENDICOLITH | 244 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (17,241, 33.6% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| FALL | 1,330 |
| PNEUMONIA | 1,273 |
| DYSPNOEA | 1,256 |
| NAUSEA | 1,186 |
| FATIGUE | 1,145 |
| VOMITING | 988 |
| DIARRHOEA | 960 |
| SOMNOLENCE | 847 |
| ASTHENIA | 789 |
| PAIN | 786 |
| PYREXIA | 785 |
| HEADACHE | 750 |
| URINARY TRACT INFECTION | 697 |
| DIZZINESS | 675 |
| INTENTIONAL OVERDOSE | 657 |
| CONSTIPATION | 614 |
| HYPOTENSION | 601 |
| WEIGHT DECREASED | 588 |
How to read melatonin FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 51,370 voluntary reports linked to melatonin (Melatonin), 2004-2025. Death is listed on 4,506 (8.8%). Hospitalization appears on 17,241 (33.6%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with melatonin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 51,859 FAERS cases (Δ 489 heavier vs melatonin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 50,521 FAERS cases (Δ 849 lighter vs melatonin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 52,302 FAERS cases (Δ 932 heavier vs melatonin); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 53,266 FAERS cases (Δ 1,896 heavier vs melatonin); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 53.3 pp vs melatonin's DEATH-HEAVY): CASELOAD · HOSP-MID.
melatonin stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.