LOW-VOLUME · SEX-BALANCED

tasimelteon Side Effects

tasimelteon (also sold as Hetlioz) is a LOW-VOLUME FAERS extract #385 of 524 by FAERS report count. Still opens on SEX-BALANCED: 57% of sex-coded reports are female (3,267 F / 2,465 M).

Data updated 2026-05-15

5,762
FAERS reports

Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.

tasimelteon reporting skew - 57% of sex-coded reports are female (3,267 F / 2,465 M). Volume band LOW-VOLUME #385 of 524 by FAERS report count; caseload WATCHLIST.

Thinner FAERS extract for tasimelteon (Hetlioz) (5,762 reports #385 of 524 by FAERS report count). 57% of sex-coded reports are female (3,267 F / 2,465 M). Sparse books still carry named reaction rows when present; not medical advice.

Counts from the openFDA FAERS extract (2014–2025). Stamps WATCHLIST · DEATH-MARKED · HOSP-LIGHT · SEX-BALANCED.

INSOMNIA leads 727 of 5,762 reports

INSOMNIA
727
MIDDLE INSOMNIA
412
SOMNOLENCE
408
HEADACHE
384
NIGHTMARE
268
ABNORMAL DREAMS
223
FATIGUE
222
THERAPEUTIC PRODUCT EFFECT DECREASED
196
SLEEP DISORDER
188
INAPPROPRIATE SCHEDULE OF PRODUCT ADMINISTRATION
179
INCORRECT PRODUCT ADMINISTRATION DURATION
165
POOR QUALITY SLEEP
154
INITIAL INSOMNIA
153
NAUSEA
145
PRODUCT DOSE OMISSION
138
DEATH
129
FEELING ABNORMAL
125
MALAISE
122

Who reports · age peak 45-64 (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 3,267 (57%)
Male 2,465 (43%)

Age peak 45-64 (1,272 reports)

0-17 25 (1%)
18-44 582 (22%)
45-64 1,272 (49%)
65-74 518 (20%)
75+ 221 (8%)

FAERS filings rising toward 2025

14
15
16
17
18
19
20
21
22
23
24
25

Reactions in Death Reports

Death appears on 166 reports (2.9% - MARKED). Reactions below co-occur in those rows only.

Reaction Reports
DEATH 129
CARDIAC ARREST 4
PNEUMONIA 4
CHRONIC OBSTRUCTIVE PULMONARY DISEASE 3
COMPLETED SUICIDE 3
SEPSIS 3
ACCIDENT 2
CARDIAC FAILURE 2
CARDIOVASCULAR DISORDER 2
DYSPHAGIA 2
HYPOTENSION 2
MYOCARDIAL INFARCTION 2
PNEUMONIA ASPIRATION 2
PULMONARY EMBOLISM 2
TOXICITY TO VARIOUS AGENTS 2
ACCIDENTAL DEATH 1
ACUTE MYOCARDIAL INFARCTION 1
AORTIC ANEURYSM 1
ARTERIOSCLEROSIS CORONARY ARTERY 1

Reactions in Hospitalization Reports

Hospitalization is lighter here (281). Reactions in that subset:

Reaction Reports
FALL 28
PRODUCT DOSE OMISSION 23
PNEUMONIA 18
DRUG DOSE OMISSION 13
INSOMNIA 12
CARDIAC DISORDER 10
SOMNOLENCE 10
URINARY TRACT INFECTION 10
MALAISE 9
SEIZURE 9
MIDDLE INSOMNIA 8
DIZZINESS 7
NIGHTMARE 7
SEPSIS 7
THROMBOSIS 7
VOMITING 7
CEREBROVASCULAR ACCIDENT 6
CHEST PAIN 6
How to read tasimelteon FAERS figures (WATCHLIST · DEATH-MARKED · HOSP-LIGHT)

FAERS holds 5,762 voluntary reports linked to tasimelteon (Hetlioz), 2014-2025. Death is listed on 166 (2.9%). Hospitalization appears on 281 (4.9%). Top co-reported indication: Non-24-Hour Sleep-Wake Disorder.

Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.

Read with tasimelteon

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-LIGHT stamps.