LOW-VOLUME · FEMALE-LED
mefenamic acid Side Effects
mefenamic acid (also sold as Ponstel) is a LOW-VOLUME FAERS extract #456 of 524 by FAERS report count. Still opens on FEMALE-LED: 78% of sex-coded reports are female (1,507 F / 427 M).
Data updated 2026-05-15
- 2,104
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
mefenamic acid reporting skew - 78% of sex-coded reports are female (1,507 F / 427 M). Volume band LOW-VOLUME #456 of 524 by FAERS report count; caseload SIGNAL.
Thinner FAERS extract for mefenamic acid (Ponstel) (2,104 reports #456 of 524 by FAERS report count). 78% of sex-coded reports are female (1,507 F / 427 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-MARKED · HOSP-HEAVY · FEMALE-LED.
NAUSEA leads 296 of 2,104 reports
FEMALE-LED reporters · age peak 18-44
Female-led reporters (78% of sex-coded rows)
Age peak 18-44 (668 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 81 reports (3.8% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| CONDITION AGGRAVATED | 8 |
| DEATH | 8 |
| DECREASED APPETITE | 8 |
| DIZZINESS | 8 |
| ARTHRALGIA | 7 |
| DIARRHOEA | 7 |
| OVERDOSE | 7 |
| SEPTIC SHOCK | 7 |
| ABDOMINAL PAIN UPPER | 6 |
| ADJUSTMENT DISORDER WITH DEPRESSED MOOD | 6 |
| ALOPECIA | 6 |
| ANXIETY | 6 |
| BREAST CANCER STAGE III | 6 |
| BURSITIS | 6 |
| COLITIS ULCERATIVE | 6 |
| CONFUSIONAL STATE | 6 |
| CONTUSION | 6 |
| CROHN^S DISEASE | 6 |
| DELIRIUM | 6 |
| DISLOCATION OF VERTEBRA | 6 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (707, 33.6% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| VOMITING | 80 |
| NAUSEA | 60 |
| DIZZINESS | 51 |
| HEADACHE | 51 |
| DIARRHOEA | 47 |
| DRUG INTERACTION | 46 |
| PYREXIA | 40 |
| RENAL FAILURE ACUTE | 37 |
| DYSPNOEA | 35 |
| TOXICITY TO VARIOUS AGENTS | 34 |
| MALAISE | 33 |
| ACUTE KIDNEY INJURY | 30 |
| ABDOMINAL DISCOMFORT | 29 |
| ABDOMINAL PAIN | 29 |
| CHILLS | 29 |
| HYPOTENSION | 29 |
| PAIN | 28 |
| ABDOMINAL PAIN UPPER | 27 |
How to read mefenamic acid FAERS figures (SIGNAL · DEATH-MARKED · HOSP-HEAVY)
FAERS holds 2,104 voluntary reports linked to mefenamic acid (Ponstel), 2004-2025. Death is listed on 81 (3.8%). Hospitalization appears on 707 (33.6%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and FEMALE-LED skew still differ by drug; not a complete safety profile.
Read with mefenamic acid
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-HEAVY stamps.
ABS(total_reports) peer at 2,157 FAERS cases (Δ 53 heavier vs mefenamic acid); DEATH-RARE · HOSP-LIGHT · SEX-BALANCED vs this page's SIGNAL · DEATH-MARKED · HOSP-HEAVY · FEMALE-LED.
ABS(total_reports) peer at 2,050 FAERS cases (Δ 54 lighter vs mefenamic acid); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-MARKED · HOSP-HEAVY · FEMALE-LED.
ABS(total_reports) peer at 2,164 FAERS cases (Δ 60 heavier vs mefenamic acid); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-MARKED · HOSP-HEAVY · FEMALE-LED.
ABS(total_reports) peer at 2,179 FAERS cases (Δ 75 heavier vs mefenamic acid); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-MARKED · HOSP-HEAVY · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 58.3 pp vs mefenamic acid's DEATH-MARKED): CASELOAD · HOSP-MID.
mefenamic acid stamps DEATH-MARKED · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.