LOW-VOLUME · SEX-BALANCED
bempedoic acid Side Effects
bempedoic acid (also sold as Nexletol) is a LOW-VOLUME FAERS extract #455 of 524 by FAERS report count. Still opens on SEX-BALANCED: 63% of sex-coded reports are female (1,103 F / 645 M).
Data updated 2026-05-15
- 2,157
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
bempedoic acid reporting skew - 63% of sex-coded reports are female (1,103 F / 645 M). Volume band LOW-VOLUME #455 of 524 by FAERS report count; caseload SIGNAL.
Thinner FAERS extract for bempedoic acid (Nexletol) (2,157 reports #455 of 524 by FAERS report count). 63% of sex-coded reports are female (1,103 F / 645 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2018–2025). Stamps SIGNAL · DEATH-RARE · HOSP-LIGHT · SEX-BALANCED.
MYALGIA leads 335 of 2,157 reports
Who reports · age peak 65-74 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 65-74 (435 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death is rare in this extract (16 / 2,157). Co-reported reactions in that thin subset:
| Reaction | Reports |
|---|---|
| DEATH | 13 |
| PAIN IN EXTREMITY | 2 |
| ASTHENIA | 1 |
| BRONCHIAL CARCINOMA | 1 |
| CARDIAC FAILURE | 1 |
| CARDIOVASCULAR DISORDER | 1 |
| CEREBRAL HAEMORRHAGE | 1 |
| CONSTIPATION | 1 |
| CYTOPENIA | 1 |
| DEHYDRATION | 1 |
| DIARRHOEA | 1 |
| DISEASE PROGRESSION | 1 |
| DISTURBANCE IN ATTENTION | 1 |
| DRUG INTERACTION | 1 |
| FALL | 1 |
| FATIGUE | 1 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 1 |
| HEAD INJURY | 1 |
| HODGKIN^S DISEASE | 1 |
Reactions in Hospitalization Reports
Hospitalization is lighter here (188). Reactions in that subset:
| Reaction | Reports |
|---|---|
| MYALGIA | 36 |
| BLOOD PRESSURE INCREASED | 25 |
| DIARRHOEA | 21 |
| NAUSEA | 18 |
| PALPITATIONS | 18 |
| MUSCULAR WEAKNESS | 17 |
| ASTHENIA | 16 |
| DEPRESSION | 16 |
| BLOOD CREATINE PHOSPHOKINASE INCREASED | 15 |
| RHABDOMYOLYSIS | 15 |
| ASPARTATE AMINOTRANSFERASE INCREASED | 13 |
| DIZZINESS | 13 |
| PAIN IN EXTREMITY | 13 |
| ARTHRALGIA | 12 |
| GAMMA-GLUTAMYLTRANSFERASE INCREASED | 12 |
| MYOGLOBIN BLOOD INCREASED | 12 |
| QUADRIPARESIS | 12 |
| HEADACHE | 11 |
| ACUTE KIDNEY INJURY | 10 |
| DYSPNOEA | 9 |
How to read bempedoic acid FAERS figures (SIGNAL · DEATH-RARE · HOSP-LIGHT)
FAERS holds 2,157 voluntary reports linked to bempedoic acid (Nexletol), 2018-2025. Death is listed on 16 (0.7%). Hospitalization appears on 188 (8.7%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.
Read with bempedoic acid
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-RARE · HOSP-LIGHT stamps.
ABS(total_reports) peer at 2,164 FAERS cases (Δ 7 heavier vs bempedoic acid); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-RARE · HOSP-LIGHT · SEX-BALANCED.
ABS(total_reports) peer at 2,179 FAERS cases (Δ 22 heavier vs bempedoic acid); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-RARE · HOSP-LIGHT · SEX-BALANCED.
ABS(total_reports) peer at 2,104 FAERS cases (Δ 53 lighter vs bempedoic acid); DEATH-MARKED · HOSP-HEAVY · FEMALE-LED vs this page's SIGNAL · DEATH-RARE · HOSP-LIGHT · SEX-BALANCED.
ABS(total_reports) peer at 2,222 FAERS cases (Δ 65 heavier vs bempedoic acid); DEATH-HEAVY · HOSP-HEAVY · MALE-LED vs this page's SIGNAL · DEATH-RARE · HOSP-LIGHT · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 61.4 pp vs bempedoic acid's DEATH-RARE): CASELOAD · HOSP-MID.
bempedoic acid stamps SIGNAL · SEX-BALANCED; class peers and methodology beat restating the same FAERS caveats on every effects URL.