HIGH-VOLUME · HOSP-HEAVY
acetaminophen Side Effects
acetaminophen (also sold as Tylenol) is HIGH-VOLUME in this FAERS book #5 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 36.0% mention hospitalization (150,224 reports).
Data updated 2026-05-15
- 417,458
- FAERS reports
FAERS voluntary reports, 1998 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
acetaminophen: 36.0% mention hospitalization (150,224 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #5 of 524 by FAERS report count.
High-report extract for acetaminophen (Tylenol): 417,458 FAERS rows (1998-2025). Top named reactions: FATIGUE, NAUSEA, HEADACHE. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1998–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
FATIGUE leads 34,487 of 417,458 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (84,726 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (58,910 reports, 14.1%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 14,850 |
| COMPLETED SUICIDE | 8,093 |
| TOXICITY TO VARIOUS AGENTS | 7,950 |
| FATIGUE | 3,857 |
| PNEUMONIA | 3,569 |
| DYSPNOEA | 3,501 |
| VOMITING | 3,339 |
| NAUSEA | 3,268 |
| DIARRHOEA | 3,160 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 2,976 |
| PYREXIA | 2,871 |
| PAIN | 2,861 |
| ASTHENIA | 2,838 |
| HEADACHE | 2,678 |
| HYPERTENSION | 2,663 |
| ARTHRALGIA | 2,510 |
| CONFUSIONAL STATE | 2,459 |
| MALAISE | 2,455 |
| DECREASED APPETITE | 2,404 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (150,224, 36.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| NAUSEA | 12,446 |
| FATIGUE | 11,938 |
| PNEUMONIA | 11,247 |
| DYSPNOEA | 11,212 |
| VOMITING | 11,193 |
| PYREXIA | 10,991 |
| PAIN | 10,516 |
| DIARRHOEA | 10,311 |
| HEADACHE | 9,240 |
| TOXICITY TO VARIOUS AGENTS | 8,965 |
| FALL | 8,648 |
| ASTHENIA | 8,352 |
| ARTHRALGIA | 7,726 |
| MALAISE | 7,238 |
| DIZZINESS | 6,552 |
| ABDOMINAL PAIN | 6,540 |
| HYPOTENSION | 6,215 |
| RASH | 6,000 |
How to read acetaminophen FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 417,458 voluntary reports linked to acetaminophen (Tylenol), 1998-2025. Death is listed on 58,910 (14.1%). Hospitalization appears on 150,224 (36.0%). Top co-reported indication: Product Used For Unknown Indication.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with acetaminophen
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 411,692 FAERS cases (Δ 5,766 lighter vs acetaminophen); DEATH-RARE · HOSP-LIGHT · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 410,053 FAERS cases (Δ 7,405 lighter vs acetaminophen); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 387,984 FAERS cases (Δ 29,474 lighter vs acetaminophen); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 366,491 FAERS cases (Δ 50,967 lighter vs acetaminophen); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 48.0 pp vs acetaminophen's DEATH-HEAVY): CASELOAD · HOSP-MID.
acetaminophen stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.