LOW-VOLUME · HOSP-HEAVY

perphenazine Side Effects

perphenazine (also sold as Trilafon) is a LOW-VOLUME FAERS extract #458 of 524 by FAERS report count. Still opens on HOSP-HEAVY: 48.2% mention hospitalization (971 reports).

Data updated 2026-05-15

2,013
FAERS reports

Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.

perphenazine: 48.2% mention hospitalization (971 reports). Death stamp DEATH-HEAVY; volume band LOW-VOLUME #458 of 524 by FAERS report count.

Thinner FAERS extract for perphenazine (Trilafon) (2,013 reports #458 of 524 by FAERS report count). 48.2% mention hospitalization (971 reports). Sparse books still carry named reaction rows when present; not medical advice.

Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.

TOXICITY TO VARIOUS AGENTS leads 274 of 2,013 reports

TOXICITY TO VARIOUS AGENTS
274
WEIGHT INCREASED
222
AKATHISIA
184
SUICIDE ATTEMPT
180
OBSESSIVE-COMPULSIVE DISORDER
163
INCREASED APPETITE
155
EUPHORIC MOOD
153
ANTIPSYCHOTIC DRUG LEVEL BELOW THERAPEUTIC
149
DISINHIBITION
148
THERAPEUTIC PRODUCT EFFECT INCOMPLETE
142
THERAPEUTIC PRODUCT EFFECT VARIABLE
140
LEUKOPENIA
139
DRUG INTERACTION
125
HYPERTENSION
117
FATIGUE
106
NAUSEA
97
TARDIVE DYSKINESIA
97

Who reports · age peak 18-44 (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 1,027 (56%)
Male 810 (44%)
Unknown 11

Age peak 18-44 (528 reports)

0-17 58 (4%)
18-44 528 (39%)
45-64 486 (36%)
65-74 145 (11%)
75+ 151 (11%)

FAERS filings rising toward 2025

2004 2025

Reactions in Death Reports

Death-mentioned subset is HEAVY here (221 reports, 11.0%). Top co-reported reactions in that subset - voluntary, not causal.

Reaction Reports
COMPLETED SUICIDE 87
TOXICITY TO VARIOUS AGENTS 53
DEATH 39
CARDIAC ARREST 29
BRADYCARDIA 17
ATRIOVENTRICULAR BLOCK 14
SEIZURE 14
HYPOTENSION 13
SOMNOLENCE 13
DYSPNOEA 10
INTENTIONAL OVERDOSE 10
BRAIN OEDEMA 9
OVERDOSE 9
CONFUSIONAL STATE 7
FALL 7
HYPERAMMONAEMIC ENCEPHALOPATHY 7
BRAIN HERNIATION 6
CARDIO-RESPIRATORY ARREST 6
HEPATOMEGALY 6

Reactions in Hospitalization Reports

Hospitalization is HEAVY (971, 48.2% of the book). Top reactions in those rows:

Reaction Reports
TOXICITY TO VARIOUS AGENTS 230
WEIGHT INCREASED 179
SUICIDE ATTEMPT 175
AKATHISIA 166
OBSESSIVE-COMPULSIVE DISORDER 152
INCREASED APPETITE 151
EUPHORIC MOOD 150
ANTIPSYCHOTIC DRUG LEVEL BELOW THERAPEUTIC 148
DISINHIBITION 148
THERAPEUTIC PRODUCT EFFECT INCOMPLETE 140
THERAPEUTIC PRODUCT EFFECT VARIABLE 139
LEUKOPENIA 129
DRUG INTERACTION 93
HYPERTENSION 90
LEUKAEMIA 82
FALL 80
OBESITY 75
How to read perphenazine FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-HEAVY)

FAERS holds 2,013 voluntary reports linked to perphenazine (Trilafon), 2004-2025. Death is listed on 221 (11.0%). Hospitalization appears on 971 (48.2%). Top co-reported indication: Product Used For Unknown Indication.

Sparse extract - named reactions and SEX-BALANCED skew still differ by drug; not a complete safety profile.

Read with perphenazine

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.