HIGH-VOLUME · DRUG DEPENDENCE
hydromorphone Side Effects
hydromorphone (also sold as Dilaudid) is HIGH-VOLUME in this FAERS book #83 of 524 by FAERS report count. Signature opener: DRUG DEPENDENCE - DRUG DEPENDENCE leads at 35,077 reports (38.7% of the book).
Data updated 2026-05-15
- 90,652
- FAERS reports
FAERS voluntary reports, 2002 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
Among 90,652 FAERS reports for hydromorphone, DRUG DEPENDENCE is the most-reported reaction (35,077). Volume band HIGH-VOLUME #83 of 524 by FAERS report count.
High-report extract for hydromorphone (Dilaudid): 90,652 FAERS rows (2002-2025). Top named reactions: DRUG DEPENDENCE, OVERDOSE, PAIN. Outcome stamps DEATH-HEAVY · HOSP-MID · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2002–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
DRUG DEPENDENCE leads 35,077 of 90,652 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (9,773 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (27,836 reports, 30.7%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 14,855 |
| TOXICITY TO VARIOUS AGENTS | 8,391 |
| OVERDOSE | 8,150 |
| DRUG DEPENDENCE | 3,639 |
| DRUG ABUSE | 1,572 |
| PAIN | 879 |
| ACCIDENTAL OVERDOSE | 745 |
| NAUSEA | 737 |
| FATIGUE | 660 |
| DRUG WITHDRAWAL SYNDROME | 642 |
| VOMITING | 578 |
| INTENTIONAL PRODUCT MISUSE | 562 |
| SEPSIS | 542 |
| DYSPNOEA | 540 |
| PNEUMONIA | 511 |
| ABDOMINAL PAIN | 489 |
| ASTHENIA | 477 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 451 |
| PYREXIA | 450 |
Reactions in Hospitalization Reports
Hospitalization mid-share (16,698, 18.4%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| PAIN | 2,423 |
| NAUSEA | 2,248 |
| DRUG DEPENDENCE | 1,856 |
| TOXICITY TO VARIOUS AGENTS | 1,649 |
| VOMITING | 1,521 |
| FATIGUE | 1,445 |
| ABDOMINAL PAIN | 1,434 |
| PYREXIA | 1,330 |
| OVERDOSE | 1,324 |
| DYSPNOEA | 1,249 |
| DIARRHOEA | 1,206 |
| PNEUMONIA | 1,204 |
| HEADACHE | 1,159 |
| MALAISE | 1,086 |
| WEIGHT DECREASED | 1,037 |
| FALL | 999 |
| ANXIETY | 992 |
| ASTHENIA | 967 |
How to read hydromorphone FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-MID)
FAERS holds 90,652 voluntary reports linked to hydromorphone (Dilaudid), 2002-2025. Death is listed on 27,836 (30.7%). Hospitalization appears on 16,698 (18.4%). Top co-reported indication: Pain.
CASELOAD books overweight common drugs and loud reporting cultures; DRUG DEPENDENCE is the page opener, not a per-patient risk.
Read with hydromorphone
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 90,121 FAERS cases (Δ 531 lighter vs hydromorphone); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 90,083 FAERS cases (Δ 569 lighter vs hydromorphone); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 91,655 FAERS cases (Δ 1,003 heavier vs hydromorphone); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 89,398 FAERS cases (Δ 1,254 lighter vs hydromorphone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 31.4 pp vs hydromorphone's DEATH-HEAVY): CASELOAD · HOSP-MID.
hydromorphone stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.