MID-VOLUME · HOSP-HEAVY
aprepitant Side Effects
aprepitant (also sold as Emend) sits MID-VOLUME #250 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 55.0% mention hospitalization (9,758 reports). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 17,740
- FAERS reports
FDA Adverse Event Reporting System extract for aprepitant. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.
aprepitant: 55.0% mention hospitalization (9,758 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #250 of 524 by FAERS report count.
Mid-book FAERS page for aprepitant (Emend) (17,740 reports). Signature HOSP-HEAVY. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (2004–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 2,145 of 17,740 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (6,016 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (2,942 reports, 16.6%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 529 |
| FATIGUE | 515 |
| VOMITING | 493 |
| DIARRHOEA | 476 |
| PYREXIA | 461 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 447 |
| HAND DEFORMITY | 416 |
| FOLLICULITIS | 409 |
| GLOSSODYNIA | 404 |
| NAUSEA | 403 |
| IMPAIRED HEALING | 401 |
| HYPERSENSITIVITY | 396 |
| DECREASED APPETITE | 394 |
| STOMATITIS | 394 |
| HELICOBACTER INFECTION | 392 |
| CONFUSIONAL STATE | 386 |
| JOINT SWELLING | 383 |
| RASH | 380 |
| INFECTION | 377 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (9,758, 55.0% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| PYREXIA | 1,317 |
| NAUSEA | 1,177 |
| FATIGUE | 1,163 |
| DIARRHOEA | 1,090 |
| VOMITING | 1,050 |
| DYSPNOEA | 1,004 |
| RASH | 920 |
| FEBRILE NEUTROPENIA | 910 |
| STOMATITIS | 814 |
| HYPERSENSITIVITY | 807 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 787 |
| PRURITUS | 778 |
| CONFUSIONAL STATE | 776 |
| ALOPECIA | 767 |
| INFUSION RELATED REACTION | 761 |
| GASTROINTESTINAL DISORDER | 757 |
| DECREASED APPETITE | 749 |
| INFECTION | 747 |
| PAIN | 731 |
How to read aprepitant FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 17,740 voluntary reports linked to aprepitant (Emend), 2004-2025. Death is listed on 2,942 (16.6%). Hospitalization appears on 9,758 (55.0%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 55.0% mention hospitalization (9,758 reports).
Read with aprepitant
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 17,680 FAERS cases (Δ 60 lighter vs aprepitant); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 17,512 FAERS cases (Δ 228 lighter vs aprepitant); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 17,969 FAERS cases (Δ 229 heavier vs aprepitant); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 17,976 FAERS cases (Δ 236 heavier vs aprepitant); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 45.5 pp vs aprepitant's DEATH-HEAVY): CASELOAD · HOSP-MID.
aprepitant stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload WATCHLIST and the label guide.