LOW-VOLUME · FEMALE-LED
chlorzoxazone Side Effects
chlorzoxazone (also sold as Parafon Forte) is a LOW-VOLUME FAERS extract #481 of 524 by FAERS report count. Still opens on FEMALE-LED: 75% of sex-coded reports are female (880 F / 288 M).
Data updated 2026-05-15
- 1,256
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
chlorzoxazone reporting skew - 75% of sex-coded reports are female (880 F / 288 M). Volume band LOW-VOLUME #481 of 524 by FAERS report count; caseload SIGNAL.
Thinner FAERS extract for chlorzoxazone (Parafon Forte) (1,256 reports #481 of 524 by FAERS report count). 75% of sex-coded reports are female (880 F / 288 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2004–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
DIZZINESS leads 94 of 1,256 reports
FEMALE-LED reporters · age peak 45-64
Female-led reporters (75% of sex-coded rows)
Age peak 45-64 (417 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (130 reports, 10.4%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 43 |
| TOXICITY TO VARIOUS AGENTS | 18 |
| DEATH | 16 |
| STEVENS-JOHNSON SYNDROME | 14 |
| CARDIO-RESPIRATORY ARREST | 9 |
| CHRONIC KIDNEY DISEASE | 7 |
| CIRCULATORY COLLAPSE | 7 |
| DEPRESSED LEVEL OF CONSCIOUSNESS | 7 |
| DIZZINESS | 7 |
| RESPIRATORY ARREST | 7 |
| RESPIRATORY DEPRESSION | 7 |
| ACUTE KIDNEY INJURY | 6 |
| HEPATOTOXICITY | 6 |
| RENAL FAILURE | 6 |
| COMA | 5 |
| MULTIPLE DRUG OVERDOSE | 5 |
| OVERDOSE | 5 |
| CARDIAC ARREST | 4 |
| HEART RATE INCREASED | 4 |
| STUPOR | 4 |
Reactions in Hospitalization Reports
Hospitalization mid-share (346, 27.5%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| PAIN | 36 |
| PNEUMONIA | 30 |
| ANXIETY | 29 |
| NAUSEA | 27 |
| FATIGUE | 25 |
| DYSPNOEA | 23 |
| TOXICITY TO VARIOUS AGENTS | 23 |
| FALL | 21 |
| ACUTE KIDNEY INJURY | 20 |
| CHEST PAIN | 15 |
| DEPRESSION | 15 |
| EMOTIONAL DISTRESS | 15 |
| VOMITING | 15 |
| CHRONIC KIDNEY DISEASE | 14 |
| DIZZINESS | 14 |
| INTENTIONAL OVERDOSE | 14 |
| SUICIDE ATTEMPT | 14 |
| DIARRHOEA | 13 |
| LOSS OF CONSCIOUSNESS | 13 |
| ABDOMINAL PAIN | 12 |
How to read chlorzoxazone FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-MID)
FAERS holds 1,256 voluntary reports linked to chlorzoxazone (Parafon Forte), 2004-2025. Death is listed on 130 (10.4%). Hospitalization appears on 346 (27.5%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and FEMALE-LED skew still differ by drug; not a complete safety profile.
Read with chlorzoxazone
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 1,275 FAERS cases (Δ 19 heavier vs chlorzoxazone); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 1,220 FAERS cases (Δ 36 lighter vs chlorzoxazone); DEATH-MARKED · HOSP-HEAVY · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 1,302 FAERS cases (Δ 46 heavier vs chlorzoxazone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 1,205 FAERS cases (Δ 51 lighter vs chlorzoxazone); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.8 pp vs chlorzoxazone's DEATH-HEAVY): CASELOAD · HOSP-MID.
chlorzoxazone stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.