MID-VOLUME · FEMALE-LED
biotin Side Effects
biotin (also sold as Vitamin B7) sits MID-VOLUME #190 of 524 by FAERS report count. Lead signal: FEMALE-LED - 90% of sex-coded reports are female (25,581 F / 2,824 M). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 29,879
- FAERS reports
FDA Adverse Event Reporting System extract for biotin. Stamp set CASELOAD · DEATH-MARKED · HOSP-MID. How figures are compiled.
biotin reporting skew - 90% of sex-coded reports are female (25,581 F / 2,824 M). Volume band MID-VOLUME #190 of 524 by FAERS report count; caseload CASELOAD.
Mid-book FAERS page for biotin (Vitamin B7) (29,879 reports). Signature FEMALE-LED. Dominant age band on file: 45-64. Educational reference only.
Counts from the openFDA FAERS extract (2004–2025). Stamps CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
FATIGUE leads 3,046 of 29,879 reports
FEMALE-LED reporters · age peak 45-64
Female-led reporters (90% of sex-coded rows)
Age peak 45-64 (7,221 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 911 reports (3.0% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| DEATH | 497 |
| NAUSEA | 118 |
| DYSPNOEA | 111 |
| VOMITING | 108 |
| MULTIPLE ORGAN DYSFUNCTION SYNDROME | 107 |
| SEPSIS | 107 |
| CONSTIPATION | 105 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 104 |
| CONDITION AGGRAVATED | 100 |
| ABDOMINAL DISTENSION | 98 |
| ANAEMIA | 98 |
| ABDOMINAL PAIN | 97 |
| HYPONATRAEMIA | 96 |
| SOMNOLENCE | 94 |
| STRESS | 92 |
| ASCITES | 87 |
| CARDIOGENIC SHOCK | 86 |
| VENTRICULAR FIBRILLATION | 85 |
| APPENDICITIS | 83 |
Reactions in Hospitalization Reports
Hospitalization mid-share (5,552, 18.6%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| FATIGUE | 620 |
| NAUSEA | 585 |
| DYSPNOEA | 500 |
| FALL | 495 |
| DIARRHOEA | 483 |
| PNEUMONIA | 453 |
| PAIN | 421 |
| VOMITING | 388 |
| HEADACHE | 367 |
| DIZZINESS | 344 |
| ASTHENIA | 337 |
| URINARY TRACT INFECTION | 321 |
| ARTHRALGIA | 306 |
| WEIGHT DECREASED | 295 |
| PAIN IN EXTREMITY | 285 |
| PYREXIA | 278 |
| MALAISE | 261 |
| CONSTIPATION | 244 |
How to read biotin FAERS figures (CASELOAD · DEATH-MARKED · HOSP-MID)
FAERS holds 29,879 voluntary reports linked to biotin (Vitamin B7), 2004-2025. Death is listed on 911 (3.0%). Hospitalization appears on 5,552 (18.6%). Top co-reported indication: Product Used For Unknown Indication.
Mid-volume extract - treat DEATH-MARKED · HOSP-MID as signal-detection rates next to 90% of sex-coded reports are female (25,581 F / 2,824 M).
Read with biotin
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 29,874 FAERS cases (Δ 5 lighter vs biotin); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 29,813 FAERS cases (Δ 66 lighter vs biotin); DEATH-MARKED · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 30,089 FAERS cases (Δ 210 heavier vs biotin); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 29,554 FAERS cases (Δ 325 lighter vs biotin); DEATH-MARKED · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 59.1 pp vs biotin's DEATH-MARKED): CASELOAD · HOSP-MID.
biotin sits in CASELOAD; high report volume tracks exposure and reporting culture more than per-patient risk. Methodology states the de-dup rules.