LOW-VOLUME · FEMALE-LED
desvenlafaxine Side Effects
desvenlafaxine (also sold as Pristiq) is a LOW-VOLUME FAERS extract #423 of 524 by FAERS report count. Still opens on FEMALE-LED: 72% of sex-coded reports are female (2,067 F / 804 M).
Data updated 2026-05-15
- 3,267
- FAERS reports
Thinner FAERS book - still a temporal association ledger, not proof of cause. Methodology.
desvenlafaxine reporting skew - 72% of sex-coded reports are female (2,067 F / 804 M). Volume band LOW-VOLUME #423 of 524 by FAERS report count; caseload SIGNAL.
Thinner FAERS extract for desvenlafaxine (Pristiq) (3,267 reports #423 of 524 by FAERS report count). 72% of sex-coded reports are female (2,067 F / 804 M). Sparse books still carry named reaction rows when present; not medical advice.
Counts from the openFDA FAERS extract (2008–2025). Stamps SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
TOXICITY TO VARIOUS AGENTS leads 233 of 3,267 reports
FEMALE-LED reporters · age peak 45-64
Female-led reporters (72% of sex-coded rows)
Age peak 45-64 (898 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (360 reports, 11.0%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 185 |
| TOXICITY TO VARIOUS AGENTS | 133 |
| DEATH | 52 |
| CARDIO-RESPIRATORY ARREST | 20 |
| OVERDOSE | 19 |
| INTENTIONAL OVERDOSE | 18 |
| PNEUMONIA | 18 |
| CARDIAC ARREST | 15 |
| DRUG INTERACTION | 13 |
| DRUG ABUSE | 9 |
| RESPIRATORY ARREST | 9 |
| BRAIN INJURY | 8 |
| CUTANEOUS VASCULITIS | 8 |
| SUSPECTED SUICIDE | 7 |
| ACCIDENTAL OVERDOSE | 6 |
| CIRCULATORY COLLAPSE | 6 |
| HYPERSENSITIVITY VASCULITIS | 6 |
| POISONING | 6 |
| ACUTE RESPIRATORY FAILURE | 5 |
| DYSPNOEA | 5 |
Reactions in Hospitalization Reports
Hospitalization mid-share (975, 29.8%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| DRUG INTERACTION | 119 |
| OVERDOSE | 115 |
| SEROTONIN SYNDROME | 90 |
| TOXICITY TO VARIOUS AGENTS | 89 |
| NAUSEA | 66 |
| DEPRESSION | 49 |
| PNEUMONIA | 49 |
| FATIGUE | 47 |
| VOMITING | 44 |
| ANXIETY | 43 |
| SUICIDE ATTEMPT | 41 |
| SEIZURE | 39 |
| SUICIDAL IDEATION | 37 |
| FALL | 35 |
| DYSPNOEA | 33 |
| HEADACHE | 33 |
| INTENTIONAL OVERDOSE | 32 |
| CONFUSIONAL STATE | 31 |
How to read desvenlafaxine FAERS figures (SIGNAL · DEATH-HEAVY · HOSP-MID)
FAERS holds 3,267 voluntary reports linked to desvenlafaxine (Pristiq), 2008-2025. Death is listed on 360 (11.0%). Hospitalization appears on 975 (29.8%). Top co-reported indication: Product Used For Unknown Indication.
Sparse extract - named reactions and FEMALE-LED skew still differ by drug; not a complete safety profile.
Read with desvenlafaxine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 3,268 FAERS cases (Δ 1 heavier vs desvenlafaxine); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 3,245 FAERS cases (Δ 22 lighter vs desvenlafaxine); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 3,228 FAERS cases (Δ 39 lighter vs desvenlafaxine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 3,219 FAERS cases (Δ 48 lighter vs desvenlafaxine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's SIGNAL · DEATH-HEAVY · HOSP-MID · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 51.1 pp vs desvenlafaxine's DEATH-HEAVY): CASELOAD · HOSP-MID.
desvenlafaxine stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload SIGNAL and the label guide.