FDA pharmacologic class
Cholinergic Muscarinic Antagonist
9 medicines are in FDA's class of cholinergic muscarinic antagonists: glycopyrrolate (Glycate), oxybutynin (Oxytrol), atropine, solifenacin, tolterodine (Detrol), trospium, darifenacin, flavoxate and 1 more; 6 combination products also contain one. 9 of the 15 are listed from generic labelers (FDA NDC Directory, October 8, 2026). The lowest pharmacy cost is oxybutynin 5 mg tablet at $0.048 per tablet (NADAC).
Which medicines are cholinergic muscarinic antagonist?
| Medicine | Brand names | Generic labelers (all forms) | Pharmacy cost | Boxed warning | Shortage | Recalls since 2012 |
|---|---|---|---|---|---|---|
| Glycopyrrolate | Glyrx-Pf, Cuvposa, Glycate | 58 labelers | $1.51 per mL 0.2 mg/mL vial | No | A presentation being discontinued | 27 |
| Oxybutynin | Oxytrol | 39 labelers | $0.048 per tablet 5 mg tablet | No | No current entry | 9 |
| Atropine | none listed | 22 labelers | $7.74 per mL 1% eye drops | No | In shortage | 15 |
| Solifenacin | none listed | 20 labelers | $0.162 per tablet 10 mg tablet | No | No current entry | 6 |
| Tolterodine | Detrol | 14 labelers | $0.268 per capsule 2 mg capsule | No | No current entry | 4 |
| Atropine and diphenoxylate | Lomotil | 19 labelers | $0.139 per tablet 2.5-0.025 mg tablet | No | No current entry | 2 |
| Trospium | none listed | 19 labelers | $0.211 per tablet 20 mg tablet | No | No current entry | 1 |
| Darifenacin | none listed | 8 labelers | $0.432 per tablet 15 mg tablet | No | No current entry | 2 |
| Trospium and xanomeline | Cobenfy | none listed | $30.13 per capsule 100 mg-20 mg capsule | No | No current entry | 0 |
| Flavoxate | none listed | 3 labelers | $0.389 per tablet 100 mg tablet | No | No current entry | 0 |
| Atropine and difenoxin | Motofen | none listed | $6.91 per tablet 1-0.025 mg tablet | No | No current entry | 0 |
| Budesonide and formoterol and glycopyrrolate | Breztri | none listed | $61.41 per gram 160-9-4.8 mcg | No | No current entry | 0 |
| Formoterol and glycopyrrolate | Bevespi | none listed | $40.86 per gram Bevespi aerosphere inhaler | No | No current entry | 1 |
| Glycopyrrolate and neostigmine methylsulfate | Prevduo | none listed | n/a | No | No current entry | 0 |
| Glycopyrronium | Qbrexza | none listed | n/a | No | No current entry | 0 |
Source: FDA Established Pharmacologic Class (NDC Directory, openFDA); CMS NADAC of October 7, 2026; FDA shortages and recalls (FDA files October 8, 2026)
What do pharmacies pay?
Each medicine's most widely listed form, per unit, in the NADAC survey: what pharmacies paid, not what a patient pays; strengths differ, so compare like with like.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price