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Medicines labeled for the same conditions

Alternatives to trimipramine

30 other medicines are given the same way (oral) and in the same FDA class as trimipramine or labeled mainly for the same use (depression); 7 are in its class, tricyclic antidepressants: amitriptyline, doxepin, nortriptyline, desipramine and 3 more; the others include 8 serotonin reuptake inhibitors, 4 serotonin and norepinephrine reuptake inhibitors and 2 aminoketones (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.03 per amitriptyline HCl 10 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as trimipramine?

The first 24 of the 30, the same class first. Depression lists all 37 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Trimipraminetricyclic antidepressantthis medicine3 labelersn/aYesNo current entry
Amitriptylinetricyclic antidepressant · same classDepression36 labelers$0.03 per tablet 10 mg tabletYesNo current entry
Doxepintricyclic antidepressant · same classDepression48 labelers$0.0779 per capsule 10 mg capsuleYesNo current entry
Nortriptylinetricyclic antidepressant · same classDepression27 labelers$0.113 per capsule 10 mg capsuleYesNo current entry
Desipraminetricyclic antidepressant · same classDepression9 labelers$0.276 per tablet 75 mg tabletYesNo current entry
Imipraminetricyclic antidepressant · same classDepression14 labelers$0.0698 per tablet 10 mg tabletYesNo current entry
Amoxapinetricyclic antidepressant · same classDepression2 labelersn/aYesNo current entry
Protriptylinetricyclic antidepressant · same classDepression2 labelers$2.71 per tablet 10 mg tabletYesNo current entry
BupropionaminoketoneDepression73 labelers$0.0785 per tablet 150 mg tabletYesNo current entry
Venlafaxineserotonin and norepinephrine reuptake inhibitorDepression62 labelers$0.0799 per capsule 75 mg capsuleYesNo current entry
Aripiprazoleatypical antipsychoticDepression47 labelers$0.110 per tablet 5 mg tabletYesNo current entry
Fluoxetineserotonin reuptake inhibitorDepression59 labelers$0.0519 per capsule 40 mg capsuleYesNo current entry
Sertralineserotonin reuptake inhibitorDepression48 labelers$0.0507 per tablet 100 mg tabletYesNo current entry
Duloxetineserotonin and norepinephrine reuptake inhibitorDepression45 labelers$0.102 per capsule 30 mg capsuleYesNo current entry
Paroxetineserotonin reuptake inhibitorDepression45 labelers$0.0611 per tablet 20 mg tabletYesNo current entry
Trazodoneserotonin reuptake inhibitorDepression38 labelers$0.0307 per tablet 50 mg tabletYesNo current entry
Escitalopramserotonin reuptake inhibitorDepression44 labelers$0.0632 per tablet 20 mg tabletYesNo current entry
MirtazapineDepression36 labelers$0.063 per tablet 15 mg tabletYesNo current entry
Citalopramserotonin reuptake inhibitorDepression35 labelers$0.026 per tablet 10 mg tabletYesNo current entry
Desvenlafaxineserotonin and norepinephrine reuptake inhibitorDepression21 labelers$0.396 per unit 50 mgYesNo current entry
VilazodoneDepression12 labelers$0.732 per tablet 10 mg tabletYesNo current entry
Fluoxetine and olanzapineserotonin reuptake inhibitorDepression3 labelers$3.44 per unit 3-25 mgYesNo current entry
Brexpiprazoleatypical antipsychoticDepression1 labeler$49.50 per tablet 0.25 mg tabletYesNo current entry
VortioxetineDepressionnone listed$17.20 per tablet 10 mg tabletYesNo current entry
Levomilnacipranserotonin and norepinephrine reuptake inhibitorDepressionnone listed$17.61 per unit 20-40 mg titration pakYesNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Trimipramine: the full record
label, generics, price, shortages, recalls