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Medicines labeled for the same conditions

Alternatives to trimethobenzamide

7 other medicines are given the same way (oral) and in the same FDA class as trimethobenzamide or labeled mainly for the same use (nausea and vomiting); 1 is in its class, antiemetics: meclizine; the others include 1 serotonin-3 receptor antagonist, 1 phenothiazine and 1 substance p/neurokinin-1 receptor antagonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0442 per meclizine 12.5 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as trimethobenzamide?

Nausea and vomiting lists all 16 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Trimethobenzamideantiemeticthis medicine4 labelersn/aNoNo current entry
Meclizineantiemetic · same classNausea and vomiting24 labelers$0.0442 per tablet 12.5 mg tabletNoNo current entry
Ondansetronserotonin-3 receptor antagonistNausea and vomiting60 labelers$0.0582 per tablet 4 mg tabletNoNo current entry
ProchlorperazinephenothiazineNausea and vomiting29 labelers$0.162 per tablet 10 mg tabletYesNo current entry
DimenhydrinateNausea and vomitingnone listed$0.0575 per tablet 50 mg tabletNoNo current entry
Aprepitantsubstance p/neurokinin-1 receptor antagonistNausea and vomiting5 labelers$46.42 per capsule 40 mg capsuleNoA presentation being discontinued
Doxylamine and pyridoxinevitamin b6 analogNausea and vomiting4 labelers$1.09 per unit 10-10 mgNoNo current entry
TradipitantNausea and vomitingnone listedn/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Trimethobenzamide: the full record
label, generics, price, shortages, recalls