Alternatives to topiramate
FDA shortage status is active for topiramate; 7 same-class SPL records are listed below for registry comparison only.
Brand: Topamax
topiramate class peers while FDA lists an active shortage
topiramate (Topamax) is on an FDA shortage listing while 7 other Anticonvulsant SPL records remain in this registry peer set (class inventory 8). Labeled indication field for topiramate: Topiramate can be used alone or with other medicines to treat certain types of seizures in people 2 years and older.
Top FAERS reaction fields for topiramate total 44,888 reports across 10 reactions, set beside carbamazepine, cenobamate, felbamate. Counts are exposure-weighted submissions, not per-patient risk.
About topiramate
Topiramate is a medicine that can help prevent seizures and migraines. It works by calming the brain.
Used for: Topiramate can be used alone or with other medicines to treat certain types of seizures in people 2 years and older. These seizures include partial-onset seizures and primary generalized tonic-clonic seizures. It also treats seizures related to Lennox-Gastaut syndrome. Topiramate can also help prevent migraine headaches in people 12 years and older.
7 Anticonvulsant peers (wide set)
carbamazepine
RxTegretol
Carbamazepine is used to treat certain types of seizures, including partial seizures and generalized tonic-clonic seizures. It can also treat mixed seizure patterns. Carbamazepine also treats the pain from trigeminal neuralgia, a nerve disorder that causes intense facial pain. It is also sometimes used for glossopharyngeal neuralgia.
cenobamate
RxXcopri
Xcopri is used to treat partial-onset seizures in adults. Partial-onset seizures start in one area of the brain. This medicine can help reduce how often you have seizures.
felbamate
RxFelbatol
Felbamate treats partial seizures in adults, both with and without generalization. It is also used as an add-on treatment for seizures related to Lennox-Gastaut syndrome in children. Because of the risk of very serious side effects, you should only use this medicine if other treatments have not worked well enough.
lacosamide
RxVimpat
Lacosamide is used to treat partial-onset seizures in patients 4 years of age and older. It is also used with other medicines to treat primary generalized tonic-clonic seizures in patients 4 years of age and older. Seizures are caused by unusual electrical activity in the brain.
lamotrigine
RxLamictal
Lamotrigine can treat epilepsy in adults and children 2 years and older. It can help with partial-onset seizures, primary generalized tonic-clonic seizures, and generalized seizures of Lennox-Gastaut syndrome. It can also be used to delay mood episodes in adults with bipolar I disorder.
levetiracetam
RxKeppra
Levetiracetam is used to treat partial-onset seizures in patients 1 month and older. It is also used with other medicines to treat myoclonic seizures in patients 12 years and older with juvenile myoclonic epilepsy. Additionally, it treats primary generalized tonic-clonic seizures in patients 6 years and older with idiopathic generalized epilepsy.
oxcarbazepine
RxTrileptal
Oxcarbazepine is used to treat partial-onset seizures. These seizures start in one part of the brain. It can be used alone or with other seizure medicines.
topiramate vs carbamazepine & cenobamate · FAERS reaction fields
FAERS top-reaction field "Migraine" shows the widest count spread between topiramate and carbamazepine, cenobamate, felbamate in this extract (4,373-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | topiramate | carbamazepine | cenobamate | felbamate |
|---|---|---|---|---|
| Headache | 6,464 | 2,241 | 317 | - |
| Nausea | 5,710 | 2,629 | 201 | 46 |
| Fatigue | 5,293 | 2,473 | 672 | 85 |
| Pain | 4,485 | 2,293 | - | - |
| Migraine | 4,373 | - | - | - |
| Dizziness | 4,123 | 2,862 | 537 | 42 |
| Seizure | 3,757 | 3,609 | 1,815 | 345 |
| Diarrhoea | 3,600 | - | - | 59 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
topiramate shortage vs Anticonvulsant peer index
Shortage status
FDA shortage listing is active for topiramate (status: To Be Discontinued). Peer rows remain a registry index, not a switch guide.
Frequently Asked Questions
Does FDA list a shortage for topiramate while peers remain indexed? ▼
Registry note: Shortage listings and peer indexes are for registry orientation only. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for topiramate: see also the generic vs brand label guide when reading Topamax SPL strings.
Read our methodology - how this data is sourced, computed, and verified.