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Medicines labeled for the same conditions

Alternatives to sumatriptan

11 other medicines are given the same way (oral) and in the same FDA class as sumatriptan or labeled mainly for the same use (migraine); 7 are in its class, serotonin-1b and serotonin-1d receptor agonists: rizatriptan, zolmitriptan, eletriptan, naratriptan and 3 more; the others include 3 calcitonin gene-related peptide receptor antagonists (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.335 per rizatriptan 10 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as sumatriptan?

Migraine lists all 27 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Sumatriptanserotonin-1b and serotonin-1d receptor agonistthis medicine22 labelers$0.302 per tablet 50 mg tabletNoNo current entry
Rizatriptanserotonin-1b and serotonin-1d receptor agonist · same classMigraine25 labelers$0.335 per tablet 10 mg tabletNoNo current entry
Zolmitriptanserotonin-1b and serotonin-1d receptor agonist · same classMigraine18 labelers$1.02 per tablet 2.5 mg tabletNoNo current entry
Eletriptanserotonin-1b and serotonin-1d receptor agonist · same classMigraine10 labelers$1.75 per tablet 40 mg tabletNoNo current entry
Naratriptanserotonin-1b and serotonin-1d receptor agonist · same classMigraine4 labelers$1.08 per tablet 2.5 mg tabletNoNo current entry
Almotriptanserotonin-1b and serotonin-1d receptor agonist · same classMigraine3 labelers$16.86 per tablet 12.5 mg tabletNoNo current entry
Frovatriptanserotonin-1b and serotonin-1d receptor agonist · same classMigraine4 labelers$2.72 per tablet 2.5 mg tabletNoA presentation being discontinued
Meloxicam and rizatriptanserotonin-1b and serotonin-1d receptor agonist · same classMigrainenone listed$122.64 per tablet 20-10 mg tabletYesNo current entry
Ubrogepantcalcitonin gene-related peptide receptor antagonistMigrainenone listed$109.11 per tablet 100 mg tabletNoNo current entry
Atogepantcalcitonin gene-related peptide receptor antagonistMigrainenone listed$38.36 per tablet 10 mg tabletNoNo current entry
Rimegepantcalcitonin gene-related peptide receptor antagonistMigrainenone listed$128.67 per tablet 75 mg tabletNoNo current entry
LasmiditanMigrainenone listed$88.77 per tablet 100 mg tabletNoA presentation being discontinued

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Sumatriptan: the full record
label, generics, price, shortages, recalls
Rizatriptan vs sumatriptan
two records side by side
Sumatriptan vs zolmitriptan
two records side by side
Eletriptan vs sumatriptan
two records side by side