HIGH-VOLUME · FEMALE-LED
sumatriptan Side Effects
sumatriptan (also sold as Imitrex) is HIGH-VOLUME in this FAERS book #170 of 524 by FAERS report count. Signature opener: FEMALE-LED - 85% of sex-coded reports are female (28,710 F / 5,040 M).
Data updated 2026-05-15
- 36,885
- FAERS reports
FAERS voluntary reports, 1996 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
sumatriptan reporting skew - 85% of sex-coded reports are female (28,710 F / 5,040 M). Volume band HIGH-VOLUME #170 of 524 by FAERS report count; caseload CASELOAD.
High-report extract for sumatriptan (Imitrex): 36,885 FAERS rows (1996-2025). Top named reactions: HEADACHE, NAUSEA, MIGRAINE. Outcome stamps DEATH-MARKED · HOSP-MID · FEMALE-LED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1996–2025). Stamps CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
HEADACHE leads 3,102 of 36,885 reports
FEMALE-LED reporters · age peak 45-64
Female-led reporters (85% of sex-coded rows)
Age peak 45-64 (10,117 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 865 reports (2.3% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| DEATH | 259 |
| COMPLETED SUICIDE | 136 |
| TOXICITY TO VARIOUS AGENTS | 99 |
| CARDIAC ARREST | 73 |
| VOMITING | 35 |
| HEADACHE | 33 |
| PAIN | 33 |
| DYSPNOEA | 32 |
| RESPIRATORY FAILURE | 30 |
| PNEUMONIA | 28 |
| RENAL FAILURE | 28 |
| FALL | 27 |
| MALAISE | 26 |
| ACUTE KIDNEY INJURY | 25 |
| LOSS OF CONSCIOUSNESS | 25 |
| OVERDOSE | 25 |
| FATIGUE | 23 |
| NAUSEA | 23 |
| ASTHENIA | 22 |
| CARDIO-RESPIRATORY ARREST | 21 |
Reactions in Hospitalization Reports
Hospitalization mid-share (6,843, 18.6%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| HEADACHE | 649 |
| NAUSEA | 614 |
| PAIN | 614 |
| MIGRAINE | 566 |
| VOMITING | 472 |
| FATIGUE | 442 |
| DYSPNOEA | 428 |
| ANXIETY | 377 |
| DIZZINESS | 377 |
| CHEST PAIN | 353 |
| FALL | 339 |
| DEPRESSION | 336 |
| DIARRHOEA | 334 |
| PNEUMONIA | 333 |
| PULMONARY EMBOLISM | 318 |
| ABDOMINAL PAIN | 292 |
| ASTHENIA | 276 |
| PYREXIA | 270 |
How to read sumatriptan FAERS figures (CASELOAD · DEATH-MARKED · HOSP-MID)
FAERS holds 36,885 voluntary reports linked to sumatriptan (Imitrex), 1996-2025. Death is listed on 865 (2.3%). Hospitalization appears on 6,843 (18.6%). Top co-reported indication: Migraine.
CASELOAD books overweight common drugs and loud reporting cultures; FEMALE-LED is the page opener, not a per-patient risk.
Read with sumatriptan
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 36,917 FAERS cases (Δ 32 heavier vs sumatriptan); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 36,931 FAERS cases (Δ 46 heavier vs sumatriptan); DEATH-HEAVY · HOSP-MID · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 37,033 FAERS cases (Δ 148 heavier vs sumatriptan); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(total_reports) peer at 37,361 FAERS cases (Δ 476 heavier vs sumatriptan); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · FEMALE-LED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 59.8 pp vs sumatriptan's DEATH-MARKED): CASELOAD · HOSP-MID.
sumatriptan sits in CASELOAD; high report volume tracks exposure and reporting culture more than per-patient risk. Methodology states the de-dup rules.