Medicines labeled for the same conditions
Alternatives to ondansetron
7 other medicines are given the same way (oral) and in the same FDA class as ondansetron or labeled mainly for the same use (nausea and vomiting); the others include 2 antiemetics, 1 phenothiazine and 1 substance p/neurokinin-1 receptor antagonist (FDA labels read October 8, 2026).
Which medicines are labeled for the same conditions as ondansetron?
Nausea and vomiting lists all 16 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Ondansetronserotonin-3 receptor antagonist | this medicine | 60 labelers | $0.0582 per tablet 4 mg tablet | No | No current entry |
| Meclizineantiemetic | Nausea and vomiting | 24 labelers | $0.0442 per tablet 12.5 mg tablet | No | No current entry |
| Prochlorperazinephenothiazine | Nausea and vomiting | 29 labelers | $0.162 per tablet 10 mg tablet | Yes | No current entry |
| Dimenhydrinate | Nausea and vomiting | none listed | $0.0575 per tablet 50 mg tablet | No | No current entry |
| Aprepitantsubstance p/neurokinin-1 receptor antagonist | Nausea and vomiting | 5 labelers | $46.42 per capsule 40 mg capsule | No | A presentation being discontinued |
| Doxylamine and pyridoxinevitamin b6 analog | Nausea and vomiting | 4 labelers | $1.09 per unit 10-10 mg | No | No current entry |
| Trimethobenzamideantiemetic | Nausea and vomiting | 4 labelers | n/a | No | No current entry |
| Tradipitant | Nausea and vomiting | none listed | n/a | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Ondansetron: the full record
- label, generics, price, shortages, recalls
- Meclizine vs ondansetron
- two records side by side
- Ondansetron vs prochlorperazine
- two records side by side
- Dimenhydrinate vs ondansetron
- two records side by side
- Aprepitant vs ondansetron
- two records side by side