Alternatives to ondansetron
2 same-class SPL records vs ondansetron - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Zofran
How to read a high-report FAERS peer set
ondansetron ranks in the upper FAERS-volume third of the corpus (#75 of 524); 2 same-class peers are listed for field comparison only. Labeled indication field for ondansetron: This medicine is used to prevent nausea and vomiting.
Top FAERS reaction fields for ondansetron total 62,322 reports across 10 reactions, set beside granisetron, palonosetron. Counts are exposure-weighted submissions, not per-patient risk.
About ondansetron
Ondansetron is a medicine that helps prevent nausea and vomiting. It is often used during cancer treatment or after surgery.
Used for: This medicine is used to prevent nausea and vomiting. It can help if you are getting chemotherapy for cancer. It also helps with nausea and vomiting after surgery or radiation.
2 5-HT3 Receptor Antagonist (Antiemetic) peers (wide set)
granisetron
RxKytril
Granisetron is used to prevent nausea and vomiting. It is for people receiving cancer therapy that causes vomiting. This includes high doses of cisplatin, radiation, total body irradiation, and fractionated abdominal radiation.
palonosetron
RxAloxi
Palonosetron is used to prevent nausea and vomiting caused by cancer chemotherapy. It can prevent these side effects from both the first treatment and any repeat treatments. Palonosetron is also used to prevent nausea and vomiting after surgery.
ondansetron vs granisetron & palonosetron · FAERS reaction fields
FAERS top-reaction field "Nausea" shows the widest count spread between ondansetron and granisetron, palonosetron in this extract (10,249-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | ondansetron | granisetron | palonosetron |
|---|---|---|---|
| Nausea | 11,554 | 1,305 | 399 |
| Fatigue | 8,199 | 549 | 249 |
| Diarrhoea | 7,791 | 709 | 246 |
| Vomiting | 7,326 | 754 | 246 |
| Death | 4,872 | 603 | 174 |
| Pyrexia | 4,788 | 641 | 164 |
| Dyspnoea | 4,707 | 592 | 194 |
| Febrile Neutropenia | 4,495 | 718 | 249 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
ondansetron FAERS volume vs class peers
FAERS volume band
ondansetron is FAERS corpus rank #75 of 524 (high volume tercile). Top-reaction field total: 62,322.
Frequently Asked Questions
Where does ondansetron sit in FAERS report volume vs 5-HT3 Receptor Antagonist (Antiemetic) peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for ondansetron: see also the generic vs brand label guide when reading Zofran SPL strings.
Read our methodology - how this data is sourced, computed, and verified.