Skip to main content

Medicines labeled for the same conditions

Alternatives to ofloxacin

9 other medicines are given the same way (ophthalmic) and in the same FDA class as ofloxacin or labeled mainly for the same use (bacterial infections); 1 is in its class, quinolone antimicrobials: ciprofloxacin; the others include 3 polymyxin-class antibacterials, 2 aminoglycoside antibacterials and 1 dihydrofolate reductase inhibitor antibacterial (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $1.50 per mL (Ciprofloxacin 0.3% eye drop) (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as ofloxacin?

Bacterial infections lists all 51 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (ophthalmic)Pharmacy costBoxed warningShortage
Ofloxacinquinolone antimicrobialthis medicine23 labelers$1.24 per mL 0.3% eye dropsNoNo current entry
Ciprofloxacinfluoroquinolone antibacterial · same classBacterial infections12 labelers$1.50 per mL 0.3% eye dropYesNo current entry
Tobramycinaminoglycoside antibacterialBacterial infections18 labelers$1.11 per mL 0.3% eye dropNoA presentation being discontinued
Dexamethasone and neomycin and polymyxin bpolymyxin-class antibacterialBacterial infections9 labelers$1.78 per mL Neomyc-polym-dexameth eye dropNoNo current entry
Gentamicinaminoglycoside antibacterialBacterial infections10 labelers$0.790 per mL 0.3% eye dropNoNo current entry
Polymyxin b and trimethoprimdihydrofolate reductase inhibitor antibacterialBacterial infections10 labelers$0.452 per mL Polymyxin b-tmp eye dropsNoNo current entry
Sulfacetamidesulfonamide antibacterialBacterial infections6 labelers$1.96 per mL 10% eye dropsNoNo current entry
Azithromycinmacrolide antimicrobialBacterial infectionsnone listed$98.51 per mL 1% eye dropsNoA presentation being discontinued
Bacitracin, hydrocortisone, neomycin and polymyxin bpolymyxin-class antibacterialBacterial infections1 labeler$5.52 per gram Neo-bacit-poly-hc eye ointmentNoNo current entry
Hydrocortisone and neomycin and polymyxin bpolymyxin-class antibacterialBacterial infections1 labeler$17.64 per mL Neomycin-poly-hc eye dropsNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Ofloxacin: the full record
label, generics, price, shortages, recalls
Ciprofloxacin vs ofloxacin
two records side by side
Ofloxacin vs tobramycin
two records side by side
Gentamicin vs ofloxacin
two records side by side