Medicines labeled for the same conditions
Alternatives to estradiol and norethindrone
5 other medicines are given the same way (oral) and in the same FDA class as estradiol and norethindrone or labeled mainly for the same use (menopause symptoms); 2 are in its class, estrogens: estrogens conjugated and bazedoxifene and estrogens conjugated; the others include 1 neurokinin 3 receptor antagonist and 1 estrogen agonist/antagonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $5.47 per conjugated estrogen 0.625 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as estradiol and norethindrone?
Menopause symptoms lists all 11 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Estradiol and norethindroneestrogen | this medicine | 7 labelers | $0.802 per tablet 0.5-0.1 mg tablet | Yes | No current entry |
| Estrogens conjugatedestrogen · same class | Osteoporosis, Menopause symptoms | 1 labeler | $5.47 per tablet 0.625 mg tablet | Yes | No current entry |
| Bazedoxifene and estrogens conjugatedestrogen agonist/antagonist · same class | Osteoporosis | none listed | $6.48 per tablet 0.45-20 mg tablet | Yes | No current entry |
| Fezolinetantneurokinin 3 receptor antagonist | Menopause symptoms | none listed | $18.58 per tablet 45 mg tablet | Yes | No current entry |
| Elinzanetant | Menopause symptoms | none listed | $9.97 per capsule 60 mg capsule | No | No current entry |
| Ospemifeneestrogen agonist/antagonist | Menopause symptoms | none listed | $8.17 per tablet 60 mg tablet | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Estradiol and norethindrone: the full record
- label, generics, price, shortages, recalls