Medicines labeled for the same conditions
Alternatives to colesevelam
15 other medicines are given the same way (oral) and in the same FDA class as colesevelam or labeled mainly for the same use (high cholesterol); 2 are in its class, bile acid sequestrants: cholestyramine and colestipol; the others include 4 HMG-CoA reductase inhibitors, 3 peroxisome proliferator receptor alpha agonists and 2 dietary cholesterol absorption inhibitors (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.658 per colestipol HCl 1 g tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as colesevelam?
High cholesterol lists all 25 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Colesevelambile acid sequestrant | this medicine | 15 labelers | $0.262 per tablet 625 mg tablet | No | No current entry |
| Cholestyraminebile acid sequestrant · same class | High cholesterol | 15 labelers | $0.834 per packet Cholestyramine packet | No | No current entry |
| Colestipolbile acid sequestrant · same class | High cholesterol | 8 labelers | $0.658 per tablet 1 g tablet | No | No current entry |
| AtorvastatinHMG-CoA reductase inhibitor | High cholesterol | 61 labelers | $0.0228 per tablet 10 mg tablet | No | No current entry |
| Fenofibrateperoxisome proliferator receptor alpha agonist | High cholesterol | 54 labelers | $0.103 per tablet 160 mg tablet | No | No current entry |
| LovastatinHMG-CoA reductase inhibitor | High cholesterol | 19 labelers | $0.0436 per tablet 20 mg tablet | No | No current entry |
| Gemfibrozilperoxisome proliferator receptor alpha agonist | High cholesterol | 27 labelers | $0.104 per tablet 600 mg tablet | Yes | A presentation being discontinued |
| PitavastatinHMG-CoA reductase inhibitor | High cholesterol | 12 labelers | $0.954 per tablet 2 mg tablet | No | No current entry |
| Ezetimibedietary cholesterol absorption inhibitor | High cholesterol | 23 labelers | $0.0667 per tablet 10 mg tablet | No | No current entry |
| Ezetimibe and simvastatindietary cholesterol absorption inhibitor | High cholesterol | 7 labelers | $0.285 per unit 10-80 mg | No | No current entry |
| Niacinnicotinic acid | High cholesterol | 13 labelers | $0.193 per tablet 500 mg tablet | No | No current entry |
| Fenofibric acidperoxisome proliferator receptor alpha agonist | High cholesterol | 7 labelers | $0.286 per capsule 135 mg capsule | No | No current entry |
| FluvastatinHMG-CoA reductase inhibitor | High cholesterol | 4 labelers | $2.88 per tablet 80 mg tablet | No | A presentation being discontinued |
| Lomitapidemicrosomal triglyceride transfer protein inhibitor | High cholesterol | none listed | n/a | Yes | No current entry |
| Bempedoic acid and ezetimibeadenosine triphosphate-citrate lyase inhibitor | High cholesterol | none listed | $13.80 per tablet 180-10 mg tablet | No | No current entry |
| Enlicitide | High cholesterol | none listed | n/a | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Colesevelam: the full record
- label, generics, price, shortages, recalls
- Colesevelam vs cholestyramine
- two records side by side
- Colesevelam vs colestipol
- two records side by side